Publications

2019

  1. Alvarez-Flores MP, Hébert A, Gouelle C, Geller S, Chudzinski-Tavassi AM, Pellerin L. Neuroprotective effect of rLosac on supplement-deprived mouse cultured cortical neurons involves maintenance of monocarboxylate transporter MCT2 protein levels. J Neurochem. Jan;148(1):80-96 (2019)

 

  1. Barreto Dos Santos N, Bonfanti AP, Rocha-E-Silva TAAD, da Silva PI Jr, da Cruz-Höfling MA, Verinaud L, Rapôso C. Venom of the Phoneutria nigriventer spider alters the cell cycle, viability, and migration of cancer cells. J Cell Physiol, v. 234, p. 1398-1415 (2019)

 

  1. Boufleur P, Sciani JM, Goldfeder M, Faria F, Branco V, Chudzinski-Tavassi AM. Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. Eur J Drug Metab Pharmacokinet. Feb;44(1):111-120 (2019)

 

  1. Boufleur P, Sciani JM, Goldfeder M, Faria F, Branco V, Chudzinski-Tavassi AM. Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. Eur J Drug Metab Pharmacokinet. Aug 21. Feb;44(1):111-120 (2019)

 

  1. Cajado-Carvalho D, da Silva CCF, Kodama RT, Mariano DOC, Pimenta DC, Duzzi B, Kuniyoshi AK, Portaro FV. Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom. Toxins (Basel). Mar 31;11(4). pii: E194 (2019)

 

  1. Charlie-Silva I, Klein A, Gomes JMM, Prado EJR, Moraes AC, Eto SF, Fernandes DC, Fagliari JJ, Junior JDC, Lima C, Lopes-Ferreira M, Conceição K, Manrique WG, Belo MAA. Acute-phase proteins during inflammatory reaction by bacterial infection: Fish-model. Sci Rep. Mar 18;9(1):4776 (2019)

 

  1. Dal Mas C, Rossato L, Shimizu T, Oliveira EB, da Silva Junior PI, Meis JF, Colombo AL, Hayashi MAF. Effects of the Natural Peptide Crotamine from a South American Rattlesnake on Candida auris, an Emergent Multidrug Antifungal Resistant Human Pathogen. Biomolecules. May 28;9(6). pii: E205 (2019)

 

  1. de Araujo CB, Calderano SG, Elias MC. The Dynamics of Replication in Trypanosoma cruzi Parasites by Single-Molecule Analysis. J Eukaryot Microbiol. May;66(3):514-518 (2019)

 

  1. de Araujo CB, de Lima LP, Calderano SG, Silva Damasceno F, Silber AM, Elias MC. Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the Trypanosoma cruzi Life Cycle and Blocks Parasite Infectivity. Antimicrob Agents Chemother. Apr 25;63(5). pii: e01806-18 (2019)

 

  1. de Lima LP, Calderano SG, da Silva MS, de Araujo CB, Vasconcelos EJR, Iwai LK, Pereira CA, Fragoso SP, Elias MC. Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi. Sci Rep. Feb 27;9(1):2888 (2019)

 

  1. Díaz-Roa A, Espinoza-Culupú A, Torres-García O, Borges MM, Avino IN, Alves FL, Miranda A, Patarroyo MA, da Silva PI Jr, Bello FJ. Sarconesin II, a New Antimicrobial Peptide Isolated from Sarconesiopsis magellanica Excretions and Secretions. Molecules. May 31;24(11). pii: E2077 (2019)

 

  1. Dos Santos TB, Soares JDM, Lima JE, Silva JC, Ivamoto ST, Baba VY, Souza SGH, Lorenzetti APR, Paschoal AR, Meda AR, Nishiyama Júnior MY, de Oliveira ÚC, Mokochinski JB, Guyot R, Junqueira-de-Azevedo ILM, Figueira AVO, Mazzafera P, Júnior OR, Vieira LGE, Pereira LFP, Domingues DS. An integrated analysis of mRNA and sRNA transcriptional profiles in Coffea arabica L. roots: insights on nitrogen starvation responses. Funct Integr Genomics. Jan;19(1):151-169 (2019)

 

  1. Esteves E, Bizzarro B, Costa FB, Ramírez-Hernández A, Peti APF, Cataneo AHD, Wowk PF, Timóteo RP, Labruna MB, Silva Junior PI, Silva CL, Faccioli LH, Fogaça AC, Sorgi CA, Sá-Nunes A. Amblyomma sculptum Salivary PGE2 Modulates the Dendritic Cell-Rickettsia rickettsii Interactions in vitro and in vivo. Frontiers in Immunology, v. 10, p. 118 (2019)

 

  1. Gren ECK, Kitano ES, Andrade-Silva D, Iwai LK, Reis MS, Menezes MC, Serrano SMT. Comparative analysis of the high molecular mass subproteomes of eight Bothrops snake venoms. Comp Biochem Physiol Part D Genomics Proteomics.Jan 30; 30:113-121 (2019)

 

  1. Kimura LF, Mattaraia VGM, Picolo G. Distinct environmental enrichment protocols reduce anxiety but differentially modulate pain sensitivity in rats. Behav Brain Res. May 17; 364:442-446 (2019)

 

  1. Liberato T, Fukushima I, Kitano ES, Serrano SMT, Chammas R, Zelanis A. Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using Terminal Amine Isotopic Labeling of Substrates. J Proteomics. 2019 Feb 10; 192:291-298 (2019)

 

  1. Lopes PH, Murakami MT, Portaro FCV, Mesquita Pasqualoto KF, van den Berg C, Tambourgi DV.Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. J Enzyme Inhib Med Chem. Dec;34(1):310-321 (2019)

 

  1. Luchini LSG, Pidde G, Squaiella Baptistao CC, Tambourgi DV. Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake. Front. Immunol. 10: 1137- 1148 (2019)

 

  1. Meneguello L, Barbosa NM, Pereira KD, Proença ARG, Tamborlin L, Simabuco FM, Iwai LK, Zanelli CF, Valentini SR, Luchessi AD. The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions. J Cell Biochem. Apr;120(4):6015-6025 (2019)

 

  1. Menezes MC, Kitano ES, Bauer VC, Oliveira AK, Cararo-Lopes E, Nishiyama MY Jr, Zelanis A, Serrano SMT. Early response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom. J Proteomics. Apr 30; 198:163-176 (2019)

 

  1. Monteiro Dos Santos J, Cardoso Dos Santos J, Marques EE, Araújo GC, Seibert CS, Lopes-Ferreira M, Lima C. Stingray (Potamotrygon rex) maturity is associated with inflammatory capacity of the venom. Toxicon. May; 163:74-83 (2019)

 

  1. Oliveira EB, Farias KJS, Gomes DL, Araújo JG, Dias da Silva W, Oliveira Rocha HA, Donadi EA, Pedrosa, MFF, Crispim JCO. Tityus serrulatus scorpion venom induces apoptosis in cervical cancer cell lines. Evidence-Based Complementary and Alternative Medicine. June 2019. (In press)

 

  1. Pereira GJV, Tavares MT, Azevedo RA, Martins BB, Cunha MR, Bhardwaj R, Cury Y, Zambelli VO, Barbosa EG, Hediger MA, Parise-Filho R. Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling. Bioorg Med Chem. 2019 May 14. pii: S0968-0896(19)30087-2 (2019)

 

  1. Reis MS, Estrela G, Ferreira CE, Barrera J. Optimal Boolean lattice-based algorithms for the U-curve optimization problem. Information Sciences 471, 97–114 (2019)

 

  1. Sidoli s, Kori y, Lopes M, Yuan ZY, Kim HJ, Kulej K, Janssen K, Agosto L, da Cunha JPC and Garcia BA. One minute analysis of histone post-translational modifications by direct infusion mass spectrometry. Genome Research, in press.

 

  1. Silva-de-França F, Villas-Boas IM, Serrano SMT, Cogliati B, Chudzinski SAA, Lopes PH, Kitano ES, Okamoto CK, Tambourgi DV. Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation. PLoS Negl Trop Dis.Jan 18;13(1):e0007017 (2019)

 

  1. Tavernelli LE, Motta MCM, Gonçalves CS, da Silva MS, Elias MC, Alonso VL, Serra E, Cribb P. Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity. Sci Rep. Jan 17;9(1):192 (2019)

 

  1. Teixeira CMM, Correa CN, Iwai LK, Ferro ES, Castro LM. Characterization of Intracellular Peptides from Zebrafish (Danio rerio) Brain. Zebrafish. Jun;16(3):240-251 (2019)

 

  1. Teixeira SC, Lopes DS, da Silva MS, da Luz FAC, Gimenes SNC, Borges BC, da Silva AA, Martins FA, Dos Santos MA, Teixeira TL, Oliveira RAO, Ávila VMR, Silva MJB, Elias MC, Martin R, da Silva CV, Knölker HJ. Pentachloropseudilin Impairs Angiogenesis by Disrupting Actin Cytoskeleton, Integrin Trafficking and Cell Cycle. Chembiochem. 2019 Apr 26 (2019)

 

  1. Vieira ML, Persson S, Lopes-Ferreira M, Romero EC, Kirchgatter K, Nascimento ALTO, Herwald H. Heparin-Binding Protein Release Is Strongly Induced by Leptospira Species and Is a Candidate for an Early Diagnostic Marker of Human Leptospirosis. J Infect Dis. Feb 23;219(6):996-1006 (2019)

 

  1. Zelanis A, Andrade-Silva D, Kitano ES, Liberato T, Fukushima I, Serrano SMT, Tashima AK. A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics. May 2019 (in press)

2018

  1. Alencar-Couto MN, Amadeu- Megale, AA, Magnoli, FC, Magalhães-Junior, MJ, da Silva, SG, Kanashiro, MM, Dias da Silva, W. Development of monoclonal antobody anti-Africam Bitis arietans snake toxin phospholipase A2. J. Toxins, 4:Issue 1, ISSN 2328-1723 (2018)

 

  1. Alves CL, Repolês BM, da Silva MS, Mendes IC, Marin PA, Aguiar PHN, Santos SDS, Franco GR, Macedo AM, Pena SDJ, Andrade LO, Guarneri AA, Tahara EB, Elias MC, Machado CR. The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi.Sci Rep. Sep 6;8(1):13335. (2018)

 

  1. Alves CRR, Faria DP, Carneiro CG, Garcez AT, Gutierrez VP, das Neves W, de Almeida NR, Cury Y, Chammas R, Brum PC. 18F-Fluoride PET/CT and 99mTc-MDP SPECT/CT can detect bone cancer at early stage in rodents. Life Sci. May 171;206:29-34 (2018)

 

  1. Amazonas DR, Portes-Junior JA, Nishiyama-Jr MY, Nicolau CA, Chalkidis HM, Mourão RHV, Grazziotin FG, Rokyta DR, Gibbs HL, Valente RH, ILM, Moura-da-Silva AM. Molecular mechanisms underlying intraspecific variation in snake venom. J Proteomics. Jun 15;181:60-72 (2018)

 

  1. Andrade-Silva D, Ashline D, Tran T, Lopes AS, Cardoso SRT, Reis MS, Zelanis A, Serrano SMT, Reinhold VN. Structures of N-Glycans of Bothrops venoms revealed as molecular signatures that contribute to venom phenotype in viperid snakes. Mol Cell Proteomics. 2018 Jul;17(7):1261-1284 (2018)

 

  1. Araldi RP, Maristela Oliveira dos Santos, Fabiane FariaBarbon, Bruna Aparecida Manjerona, Bruno Rosa Meirelles, Pedro de Oliva Neto, Pedro Ismael da Silva Júnior, Lucinéia dos Santos, Isabel Cristina Cherici Camargo, Edislane Barreiros de Souza., Analysis of antioxidant, cytotoxic and mutagenic potential of Agave sisalana Perrine extracts using Vero cells, human lymphocytes and mice polychromatic erytrocytes.  Biomedicine & Pharmacotherapy – Vol 98, Pg. 873-885 Fev  (2018)

 

  1. Atashpaz-Gargari, E.; Reis, M.S.; Barrera, J.; Braga-Neto, U.M.; Dougherty, E.R. A fast algorithm for U-curve branch-and-bound feature selection. Pattern Recognition, v. 73, p. 172–188 (2018)

 

  1. Benatti FB, Miyake CNH, Dantas WS, Zambelli VO, Shinjo SK, Pereira RMR, Silva MER, Sá-Pinto AL, Borba E, Bonfá E, Gualano B. Exercise Increases Insulin Sensitivity and Skeletal Muscle AMPK Expression in Systemic Lupus Erythematosus: A Randomized Controlled Trial. Front Immunol. Apr 27;9:906 eCollection (2018)

 

  1. Bensaoud C, Nishiyama MY Jr, Ben Hamda C, Lichtenstein F, Castro de Oliveira U, Faria F, Loiola Meirelles Junqueira-de-Azevedo I, Ghedira K, Bouattour A, M’Ghirbi Y, Chudzinski-Tavassi AM. De novo assembly and annotation of Hyalomma dromedarii tick (Acari: Ixodidae) sialotranscriptome with regard to gender differences in gene expression. Parasit Vectors.  May 24;11(1):314 (2018)

 

  1. Beraldo Neto E, Mariano DOC, Freitas LA, Dorce ALC, Martins AN, Pimenta DC, Portaro FV, Cajado-Carvalho D, Dorce VAC, Nencioni ALA. a Fraction Isolated from Tityus bahiensis Scorpion Venom, Alters Cytokines Level and Induces Seizures When Intrahippocampally Injected in Rats. Toxins (Basel). Jun 19;10(6) (2018)

 

  1. Borges AR, Toledo DA, Fermino BR, de Oliveira JC, Silber AM, Elias MC, D’Avila H, Scopel KKG. In Vitro Cellular Division of Trypanosoma abeli Reveals Two Pathways for Organelle Replication. J Eukaryot Microbiol. 2019 May;66(3):385-392 (2018)

 

  1. Cia MC, de Carvalho G, Azevedo RA, Monteiro-Vitorello CB, Souza GM, Nishiyama-Junior MY, Lembke CG, Antunes de Faria RSDC, Marques JPR1, Melotto M, Camargo LEA. Novel Insights Into The Early Stages Of Ratoon Stunting Disease Of Sugarcane Inferred From Transcript And Protein Analysis. Phytopathology V. 108, P. 8 (2018)

 

  1. Crispim M, Damasceno FS, Hernández A, Barisón MJ, Pretto Sauter I, Souza Pavani R, Santos Moura A, Pral EMF, Cortez M, Elias MC, Silber AM. The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection. PLoS Negl Trop Dis. Jan 10;12(1):e0006170 (2018)

 

  1. da Silva LB, Menezes MC, Kitano ES, Oliveira AK, Abreu AG, Souza GO, Heinemann MB, Isaac L, Fraga TR, Serrano SMT, Barbosa AS. Leptospira interrogans secreted proteases degrade extracellular Matrix and plasma proteins from the host. Front Cell Infect Microbiol. Mar 27;8:92 (2018)

 

  1. da Silva MS, Hovel-Miner GA, Briggs EM, Elias MC, McCulloch R. Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes.PLoS Pathog. Nov 15;14(11):e1007321. eCollection. Review. (2018)

 

  1. Damasceno KC, Cavalcante AK, Maziero JS, Martini GA, Ormênio MB, Mamede FC, Miranda CS, Campello FA, Izidoro JC, Rogero SO, Fungaro DA, Lopes-Ferreira M, Rogero JR. In vitro and in vivo toxicity of coal fly Ash Lechatee. Ecotoxicol. Environ. Contam. v. 13, n. 1, 2018, 73-78 (2018)

 

  1. de Luna Vitorino FN, Montoni, F, Moreno, JN, et al. FGF2 Antiproliferative Stimulation Induces Proteomic Dynamic Changes and High Expression of FOSB and JUNB in K-Ras-Driven Mouse Tumor Cells. Proteomics   Sep;18(17):e1800203. Epub 2018 Aug 14. (2018)

 

  1. De Oliveira Santos J, Zuma AA, de Luna Vitorino FN, da Cunha, JPC, de Souza, W, Motta, MCM. Trichostatin A induces Trypanosoma cruzi histone and tubulin acetylation: effects on cell division and microtubule cytoskeleton remodelling. Parasitology, v. 13, p. 1-10. (2018)

 

  1. de Oliveira UC, Nishiyama MY Jr, Dos Santos MBV, Santos-da-Silva AP, Chalkidis HM, Souza-Imberg A, Candido DM, Yamanouye N, Dorce VAC, Junqueira-de-Azevedo ILM. Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. PLoS One. Mar 21;13(3):e0193739 (2018)

 

  1. de Souza GS, Rodriguez ABF, Romano MI, Ribeiro ES, Oelemann WMR, Rocha DG, Dias da Silva W, Lassunskaia EB. Identification of the Apa protein secreted by Mycobacterium avium subsp. Paratuberculosis as a novel fecal biomarker for Johne´s disase in cattle. Pathogen and Disease, Aug 1;76(6) (2018)

 

  1. Delafontaine M, Panfil C, Spöler F, Kray S, Burgher F, Mathieu L, Blomet J, Schrage NF, Tambourgi DV. The Ex vivo Eye Irritation Test (EVEIT) model as a mean of improving venom ophthalmia understanding. Toxicon. Jun 8;150:253-260 (2018)

 

  1. Dias MH, Fonseca CS, Zeidler JD, Albuquerque LL, da Silva MS, Cararo-Lopes E, Reis MS, Noël V, Dos Santos EO, Prior IA, Armelin HA. Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. Mol Oncol. 2019 Feb;13(2):290-306 (2018)

 

  1. Díaz-Roa A, Patarroyo MA, Bello FJ, Da Silva PI Jr. Sarconesin: Sarconesiopsis magellanicaBlowfly Larval Excretions and Secretions With Antibacterial Properties. Front Microbiol. Sep 28;9:2249. eCollection (2018)

 

  1. Diniz LCL, Miranda A, da Silva PI Jr. Human Antimicrobial Peptide Isolated From Triatoma infestansHaemolymph, Trypanosoma cruzi-Transmitting Vector. Front Cell Infect Microbiol.  Oct 30;8:354. eCollection (2018)

 

  1. Diniz MRV, Paiva ALB , Guerra-Duarte C, Nishiyama Junior MY, Mudadu MA, Oliveira UC , Borges MH, Yates JR, Junqueira-de-Azevedo, ILM. An overview of Phoneutria nigriventer spider venom using combined transcriptomic and proteomic approaches. PLoS One Aug;13(8):e0200628 (2018)

 

  1. Farias IB, Morais-Zani K, Serino-Silva C, Sant’Anna SS, Rocha MMTD, Grego KF, Andrade-Silva D, Serrano SMT, Tanaka-Azevedo AM. Functional and proteomic comparison of Bothrops jararaca venom from captive specimens and the Brazilian Bothropic Reference Venom. J Proteomics. Mar 1;174:36-46 (2018)

 

  1. Ferreira Junior WA, Zaharenko AJ, Kazuma K, Picolo G, Gutierrez VP, de Freitas JC, Konno K, Cury Y. Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391. Toxins 10(1), 12. (2018)

 

  1. Florentino PTV, Real F, Orikaza CM, da Cunha JPC, Vitorino FNL, Cordero EM, Sobreira TJP, Mortara RA. A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes. Front Microbiol. Apr 10;9:693 (2018)

 

  1. Galvão da Silva BAV, Chudzinski-Tavassi AM, Pasqualoto KFM. A Combined Computer-Aided Approach to Drive the Identification of Potential Epitopes in Protein Therapeutics. J Pharm Pharm Sci. 21(1):268-285 (2018)

 

  1. Gatti da Silva GH, Jurica M, Chagas da Cunha JP, Oliveira CC, Coltri PP. Human RNF113A participates of pre-mRNA splicing in vitro. Journal of Cellular Biochemestry. v. 1, p. 1-11 (2018)

 

  1. Ikeda MAK, de Almeida JPF, Jannuzzi GP, Cronemberg-Andrade A, Torrecilhas ACT, Moretti NS, da Cunha JPC, de Almeida SR, Ferreira KS. Extracellular Vesicles From Sporothrix brasiliensis Are an Important Virulence Factor That Induce an Increase in Fungal Burden in Experimental Sporotrichosis. Frontiers in Microbiology, v. 9, p. 2286-2289 (2018)

 

  1. Ikegami A, Teixeira LFS, Braga SM, et al. Knockdown of NF-kappa B1 by shRNA Inhibits the Growth of Renal Cell Carcinoma In Vitro and In Vivo. Oncology Research. 26(5) 743-751 (2018)

 

  1. Kimura LF, Santos-Neto M, Barbaro KC, Picolo G. Potamotrygon motoro stingray venom induces both neurogenic and inflammatory pain behavior in rodents. Toxicon. Aug;150:168-174 (2018)

 

  1. Leda AR, Hunter J, Oliveira UC, Junqueira-de-Azevedo ILM, Araripe Sucupira MC, Diaz R. Sobhie Insights about minority HIV-1 strains in transmitted drug resistance mutation dynamics and disease progression Journal of Antimicrobial Chemotherapy. Jul;73(7):1930-4 (2018)

 

  1. Liberato T, Pessotti DS, Fukushima I, Kitano ES, Serrano SMT, Zelanis A. Signatures of protein expression revealed by secretome analyses of cancer associated fibroblasts and melanoma cell lines. J Proteomics. Mar 1;174:1-8 (2018)

 

  1. Lima SC, Porta LC, Lima ÁDC, Campeiro JD, Meurer Y, Teixeira NB, Duarte T, Oliveira EB, Picolo G, Godinho RO, Silva RH, Hayashi MAF.Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles. PLoS Negl Trop Dis. Aug 6;12(8):e0006700 (2018)

 

  1. Lomazi RL, ES Nishiduka, PI Silva, AK Tashima. Identification of Peptides in Spider Venom Using Mass Spectrometry (Chapter – Feb 2018 – Methods in molecular biology (Clifton, N.J.) Peptidomics, 359-367 (2018)

 

  1. Mancuso RI, Miyaji EN, Silva CCF, Portaro FV, Soares-Schanoski A, Ribeiro OG, Oliveira MLS. Impaired expression of CXCL5 and matrix metalloproteinases in the lungs of mice with high susceptibility to Streptococcus pneumoniae infection. Immun Inflamm Dis. Mar;6(1):128-142 (2018)

 

  1. Manzoni-de-Almeida D, Squaiella-Baptistão CC, Lopes PH, van den Berg CW, Tambourgi DV. Loxosceles venom Sphingomyelinase D activates human blood leukocytes: Role of the complement system. Mol Immunol. Feb;94:45-53 (2018)

 

  1. Maria DA, Will SEAL, Bosch RV, Souza JG, Sciani JM, Goldfeder MB, Rondon GG, Chudzinski-Tavassi AM. Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity. Toxicol Rep. Dec 1;6:51-63. eCollection (2018)

 

  1. Marin PA, da Silva MS, Pavani RS, Machado CR, Elias MC. Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment. Sci Rep. Mar 29;8(1):5405 (2018)

 

  1. Megale AAA, Magnoli FC, Kuniyoshi AK, Iwai LK, Tambourgi DV, Portaro FCV, da Silva WD. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities. J Venom Anim Toxins Incl Trop Dis. Dec 13; 24:38 (2018)

 

  1. Miyake CNH, Gualano B, Dantas WS, Pereira RT, Neves W, Zambelli VO, Shinjo SK, Pereira RM, Silva ER, Sá-Pinto AL, Borba E, Roschel H, Bonfá E, Benatti FB. Increased Insulin Resistance and Glucagon Levels in Mild/Inactive Systemic Lupus Erythematosus Patients Despite Normal Glucose Tolerance.  Arthritis Care Res (Hoboken). Jan;70(1):114-124 (2018)

 

  1. Oliveira DBL, Durigon GS, Mendes ÉA, Ladner JT, Andreata-Santos R, Araujo DB, Botosso VF, Paola ND, Neto DFL, Cunha MP, Braconi CT, Alves RPS, Jesus MR,Pereira LR, Melo SR, Mesquita FS, Silveira VB, Thomazelli LM, Favoretto SR, Almonfrey FB, Abdulkader RCRM, Gabrili JM, Tambourgi DV, Oliveira SF, Prieto K, Wiley MR, Ferreira LCS, Silva MV, Palacios GF, Zanotto PMA, Durigon EL. Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System. Viruses. Nov 7;10(11) (2018)

 

  1. Oliveira PRS, França FS, Villas Boas IM, Rocha MMTD, Sant’Anna SS, Bastos ML, Tambourgi DV. Snake venoms from Angola: Intra-specific variations and immunogenicity. Toxicon. 148: 85-94 (2018)

 

  1. Passaia, B.D.S., Dias, M.H., Kremer, J.L., Antonini, S.R.R., Almeida, M.Q.D., Fragoso, M.C.B.V. and Lotfi, C.F.P. TcF21/POD-1, a Transcritional regulator of sF-1/nr5a1, as a Potential Prognosis Marker in adult and Pediatric adrenocortical Tumors. Frontiers in Endocrinology, 9, p.38 (2018)

 

  1. Pavani RS, Vitarelli MO, Fernandes CAH, Mattioli FF, Morone M, Menezes MC, Fontes MRM, Cano MIN, Elias MC. Replication Protein A-1 Has a Preference for the Telomeric G-rich Sequence in Trypanosoma cruzi. J Eukaryot Microbiol. May;65(3):345-356 (2018)

 

  1. Pavon LF, Sibov TT, Caminada de Toledo SR, Mara de Oliveira D, Cabral FR, Gabriel de Souza J, Boufleur P, Marti LC, Malheiros JM, Ferreira da Cruz E, Paiva FF, Malheiros SMF, de Paiva Neto MA, Tannús A, Mascarenhas de Oliveira S, Silva NS, Cappellano AM, Petrilli AS, Chudzinski-Tavassi AM, Cavalheiro S. Establishment of primary cell culture and an intracranial xenograft model of pediatric ependymoma: a prospect for therapy development and understanding of tumor biology. Oncotarget. Apr 24;9(31):21731-21743 (2018)

 

  1. Pavon LF, Sibov TT, de Souza AV, da Cruz EF, Malheiros SMF, Cabral FR, de Souza JG, Boufleur P, de Oliveira DM, de Toledo SRC, Marti LC, Malheiros JM, Paiva FF, Tannús A, de Oliveira SM, Chudzinski-Tavassi AM, de Paiva Neto MA, Cavalheiro S. Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo. Stem Cell Res Ther. Nov 9;9(1):310 (2018)

 

  1. Pilar TV, Florentino, FR, Orikaza CM, da Cunha JPC, Vitorino FNL, Cordero EM, Sobreira TJP, Mortara RA. A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes.Frontiers in Microbiology , v. 9, p. 1-7 (2018)

 

  1. Ribeiro KS, Vasconcellos CI, Soares RP, Mendes MT, Ellis CC, Aguilera-Flores M, de Almeida IC, Schenkman S, Iwai LK, Torrecilhas AC. Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells. J Extracell Vesicles. Apr 17;7(1):1463779 (2018)

 

  1. Rostelato-Ferreira SR, Chariston A Dal Belo, Pedro I Silva Jr, Stephen Hyslop, Lea Rodrigues-Simioni, Thomaz AA Rocha-e-Silva. Presynaptic Activity of an Isolated Fraction from Rhinella Schneideri Presynaptic Activity of an Isolated Fraction from Rhinella schneideri Poison. Adv Pharm Bull. Aug; 8(3): 517–522 (2018)

 

  1. Schmidt MCB, Morais KLP, Almeida MES, Iqbal A, Goldfeder MB, Chudzinski-Tavassi AM. Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells. Cell Adh Migr. Sep 25:1-10 (2018)

 

  1. Segura-Ramírez PJ, and Silva Júnior PI. Loxosceles gaucho Spider Venom: An Untapped Source of Antimicrobial Agents Toxins 10(12), 522 (2018)

 

  1. Serrano SMT, Zelanis A, Kitano ES, Tashima AK. Analysis of the snake venom peptidome. Methods Mol Biol.1719:349-358 (2018)

 

  1. Silva MA, Lopes DS, Teixeira SC, Gimenes SNC, Azevedo FVPV, Polloni L, Borges BC, da Silva MS, Barbosa MJ, Oliveira Júnior RJ, Elias MC, da Silva CV, Yoneyama KAG, Rodrigues VM, Rodrigues RS. Genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells.Int J Biol Macromol. Oct 15;118(Pt A):311-319 (2018)

 

  1. Souza GS, Rodriguez ABF, Romário NI, Ribeiro S, Oelemann WMR, Rocha DG, Dias da Silva, W. Lassunskaia EB. Identification of the Apa protein secreted by Mycobacterium avium subsp. Paratuberculosis as a novel fecal biomarker for Johne´s disase in cattle. Pathogen and Disease, Volume 76, Issue 6, August fty063. (2018)

 

  1. Squaiella-Baptistão CC, Magnoli FC, Marcelino JR, Sant’Anna OA, Tambourgi DV. Quality of horse F(ab’)2 antitoxins and anti-rabies immunoglobulins: protein content and anticomplementary activity. J Venom Anim Toxins Incl Trop Dis, vol.24, 16 (2018)

 

  1. Squaiella-Baptistão CC, Sant’Anna OA, Marcelino JR, Tambourgi DV. The history of antivenoms development: Beyond Calmette and Vital Brazil. Toxicon 150: 86-95 (2018)

 

  1. Torres MDT, Pedron CN, Higashikuni Y, Kramer RM, Cardoso MH, Oshiro KGN, Franco OL, Silva Junior PI, Silva FD, Oliveira Junior VX, Lu TK, de la Fuente-Nunez C. Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. CommunDec 7;1:221. eCollection (2018)

 

  1. Torres-Bonilla KA, Andrade-Silva D, Serrano SM, Hyslop S. Comp. Biochemical characterization of venom from Pseudoboa neuwiedii (Neuwied􏰀s false boa; Xenodontinae; Pseudoboini). Biochem. Physiol. C. Toxicol. Pharmacol. Jun 30;213:27-38 (2018)

 

  1. Valente RH, Luna MS, Oliveira UC, Nishiyama Junior MY, Junqueira-de-Azevedo ILM, Portes Júnior JÁ, Clissa PB, Viana LG, Sanches L, Moura-da-Silva AM, Perales JEA, Yamanouye N. Bothrops jararaca accessory venom gland is an ancillary source of toxins to the snakeJournal of Proteomics. Apr;177:137-47 (2018)

 

  1. Vitorino; F.N.L.; Montoni, F.; Moreno, J.N.; Souza, B.F.; Lopes, M.C.; Cordeiro, B.; Fonseca, C.S.; Gilmore, J.M.; Sardiu, M.I.; Reis, M.S.; Florens, L.A.; Washburn, M.P.; Armelin, H.A.; da Cunha, J.P.C. FGF-2 antiproliferative stimulus induces proteomics dynamics changes and high expression of fosB and junB in K-Ras-driven mouse tumor cells. Proteomics. 2018 Jul 23 v. 23, p. 1800203. (2018)

 

  1. Walter, J.M.; Lopes, F.A.C.; Lopes-Ferreira, M.; Vidal, L.M.; Leomil, L.; Melo, F.; De Azevedo, Girlene S.; Oliveira, R.M.S.; Medeirtos, A.J.; Melo, A.S.O.; De Rezende, C.E.; Tanuri, A.; Thompson, F.L. Occurrence of Harmful Cyanobacteria in Drinking Water from a Severely Drought-Impacted Semi-arid Region. Frontiers in Microbiology, v. 9, p. 176-185 (2018)

2017

  1. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press (2016).
  2. Abreu TF, Sumitomo BN, Nishiyama MY Jr, Oliveira UC, Souza GH, Kitano ES, Zelanis A, Serrano SM, Junqueira-de-Azevedo I, Silva PI Jr, Tashima AK. Peptidomics of Acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity. J Proteomics 151:232-242 (2017).
  3. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press.
  4. Araujo TL, Zeidler JD, Oliveira PV, Dias MH, Armelin HA, Laurindo FR. Protein disulfide isomerase externalization in endothelial cells follows classical and unconventional routes. Free Radic Biol Med.103:199-208 (2017).
  5. Campos JC, Queliconi BB, Bozi LH; Bechara LR, Dourado PM, Andres A M, Jannig PR, Gomes KM, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB. Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy (Georgetown, TX), in press.
  6. Candido-Ferreira IL, Kronenberger T, Sayegh RS, Batista IF, da Silva Junior PI. Evidence of an antimicrobial peptide signature encrypted in HECT E3 ubiquitin ligases Frontiers Immunology 9; 7:664 (2017).
  7. Chaves AF, Castilho DG, Navarro MV, Oliveira AK, Serrano SM, Tashima AK, Batista WL. Phosphosite-specific regulation of the oxidative-stress response of Paracoccidioides brasiliensis: a shotgun phosphoproteomic analysis. Microbes Infect. 19(1):34-46 (2017).
  8. da Silva MS, Munoz, PA, Armelin HA, Elias MC. Differences in the detection of BrdU/Edu incorporation assays alter the calculation for G1, S, and G2 phases of the cell cycle in Trypanosomatids. J Eukaryot Micorbiol 4: 1-14 (2017).
  9. da Silva MS, Segatto M, Pavani RS, Guitierrez-Rodrigues F, Bispo VD, de Medeiros MH, Calado RT, Elias MC, Cano MI. Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites. Biochim Biophys Acta 1864 (1): 138-150 (2017).
  10. Di Genova BM, da Silva RC, da Cunha JP, Gargantini PR, Mortara RA, Tonelli RR. Protein SUMOylation is Involved in Cell-cycle Progression and Cell Morphology in Giardia lamblia. J Eukaryot Microbiol. Nov 19 in press.
  11. Dias RG, Sampaio SC, Sant’Anna MB, Cunha FQ, Gutiérrez JM, Lomonte B, Cury Y, Picolo G. Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect. J. Venom Anim Toxins Incl Trop Dis. 23;23:18 (2017).
  12. Félix-Silva J, Gomes JA, Xavier-Santos JB, Passos JG, Silva-Junior AA, Tambourgi DV, Fernandes-Pedrosa M. Inhibition of local effects induced by Bothrops erythromelas snake venom: Assessment of the effectiveness of Brazilian polyvalent bothropic antivenom and aqueous leaf extract of Jatropha gossypiifolia. Toxicon, 125:74-83 (2017).
  13. Folle AM, Kitano ES, Lima A, Gil M, Cucher M, Mourglia-Ettlin G, Iwai LK, Rosenzvit M, Batthyány C, Ferreira AM. Characterisation of Antigen B Protein Species Present in the Hydatid Cyst Fluid of Echinococcus canadensis G7 Genotype. PLoS Negl Trop Dis. 3;11(1):e0005250 (2017).
  14. Gonzales-Zubiate FA, Okuda EK, Da Cunha JP, Oliveira CC. Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. J Biol Chem. jbc.M116.772376. in press
  15. Grund LZ, Novaski I, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R. Autoimmunity. 50(2):86-101 (2017).
  16. Iqbal A, Goldfeder MB, Marques-Porto R, Asif H, Souza JG, Faria F, Chudzinski-Tavassi AM. Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. Sci Rep. 3;7(1):1431 (2017).
  17. Katz ISS, Dias MH, Lima IF, Chaves LB, Ribeiro OG, Scheffer KC, Iwai LK. Large protein as a potential target for use in rabies diagnostic, Acta Virologica in press.
  18. Komegae EN, Souza TA, Grund LZ, Lima C, Lopes-Ferreira M. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis. PLoS One. 24;12(2):e0171796 (2017).
  19. Lopes PH, Rocha MT, Kuniyoshi AK, Portaro FV, Gonçalves LRC. Edema and Nociception Induced by Philodryas patagoniensis Venom in Mice: A Pharmacological Evaluation with Implications for the Accident Treatment. J. Pharmacol. Exp. Ther. 361(3): 349-354 (2017)
  20. Miyake CN, Gualano B, Dantas WS, Pereira RT, Neves W, Zambelli VO, Shinjo SK, Pereira RM, Silva ER, Sá-Pinto AL, Borba E, Roschel H, Bonfá E, Benatti FB. Increased insulin resistance and glucagon levels in mild/inactive systemic lupus patients despite normal glucose tolerance. Arthritis Care Res (Hoboken). 20 (2017).
  21. Monte ER, Rossato C, Llanos RP, Russo LC, de Castro LM, Gozzo FC, de Araujo CB, Peron JP, Sant’Anna OA, Ferro ES, Rioli V. Interferon-gamma activity is potentiated by an intracellular peptide derived from the human 19S ATPase regulatory subunit 4 of the proteasome. J Proteomics 16; 151:74-82 (2017).
  22. Nicolau CA, Carvalho PC, Junqueira-de-Azevedo IL, Teixeira-Ferreira A, Junqueira M, Perales J, Neves-Ferreira AG, Valente RH. An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca. J Proteomics. 16;151:214-231 (2017).
  23. Okamoto CK, van den Berg CW, Masashi M, Gonçalves-de-Andrade RM, Tambourgi DV. Tetracycline Reduces Kidney Damage Induced by Loxosceles Spider Venom. Toxins (Basel). 2;9(3) (2017).
  24. Pedron CN, Torres MDT, da Silva Lima JA, Silva PI, Silva FD, Oliveira VX. Novel designed VmCT1 analogs with increased antimicrobial activity. European Journal of Medicinal Chemistry 126, 456-463 (2017).
  25. Perazzo J, Lima C, Heras M, Bardají E, Lopes-Ferreira M, Castanho M. Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action. ACS Chem Neurosci in press.
  26. Russo LC, Araujo CB, Iwai LK, Ferro ES, Forti FL. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells. J Proteomics. 16;151:24-32 (2017).
  27. Sousa LF, Portes-Junior JA, Nicolau CA, Bernardoni JL, Nishiyama-Jr MY, Amazonas DR, Freitas-de-Sousa LA, Mourão RH, Chalkidis HM, Valente RH, Moura-da-Silva AM. Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon. Journal of Proteomics (Print), v. 1, p. 1, 2017. J Proteomics. 21;159:32-46 (2017).
  28. Teixiera SC, Lopes DS, Gimenes SN, Teixiera TL, da Silva MS, Brígido RT, da Luz FA, da Silva AA, Silva MA, Florentino PV, Tavares PC, dos Santos MA, Ávila VM, Silva MJ, Elias MC, Mortara RA, da Silva CV. Mechanistic Insights into the Anti-angiogenic Activity of Trypanosoma cruzi Protein 21 and its Potential Impact on the Onset of Chagasic Cardiomyopathy. Sci Rep 7:44978 (2017).
  29. Torres MDT, Pedron CN, Araújo I, Silva PI, Silva FD, Oliveira VX. Decoralin Analogs with Increased Resistance to Degradation and Lower Hemolytic Activity ChemistrySelect 2 (1), 18-23 (2017)
  30. Zambelli VO, Chioato L, Gutierrez VP, Ward RJ, Cury Y.Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2. J Venom Anim Toxins Incl Trop Dis. 10;23:7 (2017).

2016

  1. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press (2016).
  2. Andrade-Silva D, Zelanis A, Kitano ES, Junqueira-de-Azevedo IL, Reis MS, Lopes AS, Serrano SM. Proteomic and glycoproteomic profilings reveal that post-translational modifications of toxins contribute to venom phenotype in snakes. J Proteome Res. 15(8):2658-75 (2016).
  3. Augusto-de-Oliveira C, Stuginski DR, Kitano ES, Andrade-Silva D, Liberato T, Fukushima I, Serrano SM, Zelanis A. Dynamic rearrangement in snake venom gland proteome: insights into Bothrops jararaca intraspecific venom variation. J Proteome Res. 15(10):3752-3762 (2016).
  4. Bernardes-Oliveira E, Gomes DL, Palomino GM, Farias KJS, Dias da Silva W, Rocha HAO, Gonçalves AK, Fernandes-Pedrosa MF, Crispim JCO. Bothrops jararaca and Bothrops erythromelas Snake Venoms Promote Cell Cycle Arrest and Induce Apoptosis via the Mitochondrial Depolarization of Cervical Cancer Cells. Evidence-Based Complementary and Alternative Medicine Volume Article ID 1574971 (2016).
  5. Bertholim L, Zelanis A, Oliveira AK, Serrano SM. Proteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase. Amino Acids 48(5):1331-5 (2016).
  6. Bosch RV, Alvarez-Flores MP, Maria DA, Chudzinski-Tavassi AM. Hemolin triggers cell survival on fibroblasts in response to serum deprivation by inhibition of apoptosis. Biomedicine & Pharmacotherapy 82: 537-546 (2016).
  7. Branco VG, Iqbal A, Alvarez-Flores MP, Sciani JM, de Andrade SA, Iwai LK, Serrano SM, Chudzinski-Tavassi AM. Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo. Biochim Biophys Acta. 1864(10):1428-35 (2016).
  8. Bressan E, Touska F, Vetter I, Kistner K, Kichko TI, Teixeira NB, Picolo G, Cury Y, Lewis RJ, Fischer MJ, Zimmermann K, Reeh PW. Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia. Pain. 157(11):2504-2516 (2016).
  9. Brigatte P, Faiad OJ, Ferreira Nocelli RC, Landgraf RG, Palma MS, Cury Y, Curi R, Sampaio SC. Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4. Mediators Inflamm. 2457532 (2016).
  10. Cajado-Carvalho D, Kuniyoshi AK, Duzzi B, Iwai LK, Oliveira ÚC, Junqueira de Azevedo IL, Kodama RT, Portaro FV. Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase. Toxins (Basel). 24;8(12): 348 (2016).
  11. Campos PF, Andrade-Silva D, Zelanis A, Paes Leme AF, Rocha MM, Menezes MC, Serrano SM, Junqueira-de-Azevedo Ide L. Trends in the evolution of snake toxins underscored by an integrative omics approach to profile the venom of the colubrid Phalotris mertensi. Genome Biol Evol. 8(8):2266-87 (2016).
  12. Carlstron JP, Verreschi DC, Batista IDC, Tsubouchi BD, de Abreu BCG, Mastantuno D, Ito DT, Ramos PW, Szczygiel NL, Chudzinski-Tavassi AM, Cruz JÁ, Barazzone GC, de Andrade AS. Segregation and packaging of Chemical Products: Deploying a Secure System in the Protein Chemistry Facility of the Laboratory of Biochemistry and Biophysics – Butantan Institute. Orbital-Electronic Journal Of Chemistry v. 8 Ed. 3 p. 218-225 (2016).
  13. Castiblanco-Valencia MM, Fraga TR, Pagotto AH, de Toledo Serrano SM, Abreu PA, Barbosa AS, Isaac L. Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion. Immunobiology 221(5):679-89 (2016).
  14. Chaparro, E.; da Silva Junior, P. I.Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis. International Journal of Antimicrobial Agents Volume: 48 Issue: 3 Pages: 277-285 Published: SEP 2016
  15. Chudzinski-Tavassi AM, Morais KL, Pacheco MT, Pasqualoto KFM, de Souza JG. Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates. Biomed Pharmacother 77:14-9. (2016). Review.
  16. Corrêa MA, Okamoto CK, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. PLoS One 11(4):e0153090 (2016).
  17. Cristina de Oliveira-Lima K, Farsky SH, Lopes PH, de Andrade RM, van den Berg CW, Tambourgi DV. Microcirculation abnormalities provoked by Loxosceles spiders’ envenomation. Toxicon 116: 35-42 (2016).
  18. de Jesus TC, Nunes VS, Lopes Mde C, Martil DE, Iwai LK, Moretti NS, Machado FC, de Lima-Stein ML, Thiemann OH, Elias MC, Janzen C, Schenkman S, da Cunha JP Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi. J Proteome Res.15(6):2039-51 (2016).
  19. de Souza JG, Morais KL, Anglés-Cano E, Boufleur P, de Mello ES, Maria DA, Origassa CS, de Campos Zampolli H, Câmara NO, Berra CM, Bosch RV, Chudzinski-Tavassi AM.Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model. Oncotarget. 20;7(38):62255-62266 (2016).
  20. Dias, Matheus H.; Kitano, Eduardo S.; Zelanis, Andre; et al.Proteomics and drug discovery in câncer. Drug Discovery Today Volume: 21 Issue: 2 Pages: 264-277 Published: FEB 2016
  21. Duzzi B, Cajado-Carvalho D, Kuniyoshi AK, Kodama RT, Gozzo FC, Fioramonte M, Tambourgi DV, Portaro FV, Rioli V. [des-Arg(1)] -Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom. Peptides 80:18-24 (2016).
  22. Elias MC, Floeter-Winter LM, Mena-Chalco JP. The dynamics of Brazilian protozoology over the past century. Mem Inst Oswaldo Cruz 111(1): 67-74 (2016).
  23. Garcia PRAF, Bicev RN, Oliveira CLP, Sant’Anna AO, Fantini MCA. Protein encapsulation in SBA-15 with expanded pores. Microporous and Mesoporous Materials 235. 59 e 68 (2016).
  24. Girard, Richard M. B. M.; Crispim, Marcell; Stolic, Ivana; et al. An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells. Antimicrobial Agents and Chemotherapy Volume: 60 Issue: 10 Pages: 5867-5877 Published: OCT 2016
  25. Guidolin FR, Caricati CP, Marcelino JR, da Silva WD. Development of Equine IgG Antivenoms against Major Snake Groups in Mozambique. PLoS Negl Trop Dis. Jan 5;10(1):e0004325 (2016).
  26. Guidolin FR, Tambourgi DV, Guidolin R, Marcelino JR, Okamoto CK, Magnoli FC, Queiroz GP, Dias da Silva W.Characterization of anti-crotalic antibodies. Toxicon. 2013 May; 66:7-17.
  27. Guirro ECBP, Perotta JH, de Paula M, Cury Y, Valadão CAA. Clinical, behavioral and antinociceptive effects of crotalphine in horses. Ciência Rural 46 (4): 694-699 (2016).
  28. Junqueira-de-Azevedo IL, Campos PF, Ching AT, Mackessy SP. Colubrid Venom Composition: An -Omics Perspective. Toxins (Basel). Review. 23;8(8):230 (2016).
  29. Leandro de Jesus TC, Calderano SG, Vitorino FN, Llanos RP, Lopes MC, de Araújo CB, Thiemman OH, Reis MD, Elias MC, Chagas da Cunha JP. Quantitative Proteomic Analysis of Replicative and Nonreplicative Forms Reveals Important Insights into Chromatin Biology of Trypanosoma cruzi. Mol Cell Mol Cell Proteomics. 16(1):23-38201 (2016).
  30. Liberato T, Troncone LR, Yamashiro ET, Serrano SM, Zelanis A. High-resolution proteomic profiling of spider venom: expanding the toxin diversity of Phoneutria nigriventer venom. Amino Acids 48(3):901-6 (2016).
  31. Lopes-Ferreira M, Sosa-Rosales I, Bruni FM, Ramos AD, Vieira Portaro FC, Conceição K, Lima C. Analysis of the intersexual variation in Thalassophryne maculosa fish venoms. Toxicon. 1;115:70-80 (2016).
  32. Menezes MC, Imbert L, Kitano ES, Vernet T, Serrano SM. Recombinant expression of the precursor of the hemorrhagic metalloproteinase HF3 and its non-catalytic domains using a cell-free synthesis system. Amino Acids. 48(9):2205-14 (2016).
  33. Morais KL, Pacheco MT, Berra CM, Bosch RV, Sciani JM, Chammas R, de Freitas Saito R, Iqbal A, Chudzinski-Tavassi AM. Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell. Mol Cell Biochem 415(1-2):119-31 (2016).
  34. Myamoto DT, Pidde-Queiroz G, Gonçalves-de-Andrade RM, Pedroso A, van den Berg CW, Tambourgi DV. Characterization of a Gene Coding for the Complement System Component FB from Loxosceles laeta Spider Venom Glands. PLoS One 11(1): e0146992 (2016).
  35. Myamoto DT, Pidde-Queiroz G, Pedroso A, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. Characterization of the gene-encoding component C3 of the complement system from the spider Loxosceles laeta venom glands: Phylogenetic implications. Immunobiology 221(9): 953–963 (2016).
  36. Pacheco MT, Morais KL, Berra CM, Demasi M, Sciani JM, Branco VG, Bosch RV, Iqbal A, Chudzinski-Tavassi AM. Specific role of cytoplasmic dynein in the mechanism of action of na antitumor molecule, Amblyomin-X. Exp Cell Res.15;340(2):248-58 (2016).
  37. Pasqualoto KF, Balan A, Barreto SA, Simons SM, Chudzinski-Tavassi AM. Structural findings and molecular modeling approach of a TFPI-like inhibitor. Protein and peptide letters 21(5), 452-457 (2014).
  38. Pavani, Raphael Souza; da Silva, Marcelo Santos; Henrique Fernandes, Carlos Alexandre; et al. Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. Plos Neglected Tropical Diseases Volume: 10 Issue: 12 Published: DEC 2016
  39. Pavon LF, Sibov TT, de Oliveira DM, Marti LC, Cabral FR, de Souza JG, Boufleur P, Malheiros SMF, Neto MAD, da Cruz EF, Chudzinski-Tavassi AM, Cavalheiro S. Mesenchymal stem cell-like properties of CD133(+) glioblastoma-initiating cells. Oncotarget v. 7. 40546-40557 (2016).
  40. Perazzo J, Lopes-Ferreira M, Sá Santos S, Serrano I, Pinto A, Lima C, Bardaji E, Tavares I, Heras M, Conceição K, Castanho MA. Endothelium-Mediated Action of Analogues of the Endogenous Neuropeptide Kyotorphin (Tyrosil-Arginine): Mechanistic Insights from Permeation and Effects on Microcirculation. ACS Chem Neurosci. 17;7(8):1130-40 (2016).
  41. Rabaça AN, Arruda DC, Figueiredo CR, Massaoka MH, Farias CF, Tada DB, Maia VC, Silva Junior PI, Girola N, Real F, Mortara RA, Polonelli L, Travassos LR. AC‐1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model. FEBS Open Bio 6 (9), 885-901 (2016).
  42. Ramos HR, Junqueira-de-Azevedo IL, Novo JB, Castro K, Duarte CG, Machado-deÁvila RA, Chavez-Olortegui C, Ho PL. A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom. PLoS Negl Trop Dis 10(3):e0004484 (2016).
  43. Sato AC, Bosch RV, Will SE, Alvarez-Flores MP, Goldfeder MB, Pasqualoto KF, da Silva BA, de Andrade SA, Chudzinski-Tavassi AM. Exploring the in vivo wound healing effects of a recombinant hemolin from the caterpillar Lonomia obliqua. J Venom Anim Toxins Incl Trop Dis. 21;22:36 (2016).
  44. Sayegh RSR, Batista IFC, de Melo RL, Riske KA, Daffre S, Montich G and da Silva Junior PI. Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles. PloS one 11 (12), e016795 (2016).
  45. Scaramuzzi K, Tanaka GD, Neto FM, Garcia PR, Gabrili JJ, Oliveira DC, Tambourgi DV, Mussalem JS, Paixão-Cavalcante D, D’Azeredo Orlando MT, Botosso VF, Oliveira CL, Fantini MC, Sant’Anna AO. Nanostructured SBA-15 silica: An effective protective vehicle to oral hepatitis B vaccine immunization. Nanomedicine12 (8): 2241-2250 (2016).
  46. Silva TA, Smuczek B, Valadão IC, Dzik LM, Iglesia RP, Cruz MC, Zelanis A, de Siqueira AS, Serrano SM, Goldberg GS, Jaeger RG, Freitas VM. AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility. Oncotarget. 7(31):49998-50016 (2016).
  47. Silva-Álvarez V, Folle AM, Ramos AL, Kitano ES, Iwai LK, Corraliza I, Córsico B, Ferreira AM. Echinococcus granulosus Antigen B binds to monocytes and macrophages modulating cell response to inflammation. Parasit Vectors. 4;9:69 (2016).
  48. Tanaka GD, Sant’Anna OA, Marcelino JR, Lustoza da Luz AC, Teixeira da Rocha MM, Tambourgi DV. Micrurus snake species: Venom immunogenicity, antiserum crossreactivity and neutralization potential. Toxicon 7: 59-68 (2016).
  49. Zambelli VO, Pasqualoto KF, Picolo G, Chudzinski-Tavassi AM, Cury Y. Harnessing the knowledge of animal toxins to generate drugs. Pharmacol Res. pii: S1043- 6618(16)00015-3. (2016). Review.
  50. Zelanis A, Menezes MC, Kitano ES, Liberato T, Tashima AK, Pinto AF, Sherman NE, Ho PL, Fox JW, Serrano SM. Proteomic identification of gender molecular markers in Bothrops jararaca venom. J Proteomics 139:26-37 (2016).

2015

  • Akamatsu MA, Nishiyama MY Jr, Morone M, Oliveira UC, Bezerra MF, Sakauchi MA, Raw I, Junqueira de Azevedo IL, Kitajima JP, Carvalho E, Ho PL Whole-Genome Sequence of a Bordetella pertussis Brazilian Vaccine Strain. Genome Announc. 3(1) pii: e01570-14 (2015).
  • Alberto-Silva C, Gilio JM, Portaro FC, Querobino SM, Camargo AC. Angiotensinconverting enzyme inhibitors of Bothrops jararaca snake venom affect the structure of mice seminiferous epithelium. J Venom Anim Toxins Incl Trop Dis 4; 21:27 (2015).
  • Almeida AM, Foronda L. Ação Educativa do Museu Histórico do Instituto Butantan: reflexões sobre os últimos três anos [Educational action of the Historical Museum of Instituto Butantan: reflexions from the last three years]. Revista Museologia & Interdisciplinaridade, 3:149-163 (2015)
  • Amorim A, Prado MX, De Oliveira UC, Faria F, Pasqualoto KFM, Junqueira-De-Azevedo ILM, Chudzinski-Tavassi AM. Transcripts involved in hemostasis: Exploring salivar complexes from Haementeria vizottoi leeches through transcriptomics, phylogenetic studies and structural features. Toxicon (Oxford), 106, p. 20-29 (2015).
  • Calderano SG, Drosopoulos WC, Quaresma MM, Marques CA, Kosiyatrakul S, McCulloch R, Elias MC Single molecule analysis of Trypanosoma brucei DNA replication dynamics. Nucleic Acids Research 43(5): 2655-2665 (2015).
  • Campeiro JD, Neshich IP, Sant’Anna OA, Lopes R, Ianzer D, Assakura MT, Neshich G, Hayashi MA. Identification of snake bradykinin-potentiating peptides (BPPs)-simile sequences in rat brain – Potential BPP-like precursor protein? Biochem Pharmacol.2015 Jun 3. Aug 1;96(3):202-15
  • Catta-Preta CM1, Brum FL1, da Silva CC1, Zuma AA1, Elias MC2, de Souza W3, Schenkman S4, Motta MC1. Endosymbiosis in trypanosomatid protozoa: the bacterium division is controlled during the host cell cycle. Front Microbiol. 2015 Jun 2; 6:520. eCollection (2015).
  • Chudzinski-Tavassi AM, Picolo G, Pasqualoto KFM, Cury Y. Vital Brasil e o pioneirismo na utilização de venenos animais como agentes terapêuticos. Cadernos de História da Ciência, v. 10, p. 13-32 (2015).
  • Costa ET, Barnabé GF, Li M, Dias AA, Machado TR, Asprino PF, Cavalher FP, Ferreira EN, Del Mar Inda M, Nagai MH, Malnic B, Duarte ML, Leite KR, de Barros AC, Carraro DM, Chammas R, Armelin HA, Cavenee W, Furnari F, Camargo AA Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals. Oncogene 34(10):1270-9 (2015).
  • Dantas WS, Marcondes JA, Shinjo SK, Perandini LA, Zambelli VO, Neves WD, Barcellos CR, Rocha MP, Yance Vdos R, Pereira RT, Murai IH, Pinto AL, Roschel H, Gualano B. GLUT4 translocation is not impaired after acute exercise in skeletal muscle of women with obesity and polycystic ovary syndrome. Obesity (Silver Spring) 23(11):2207-15 (2015).
  • de Oliveira UC, Candido DM, Coronado Dorce VA, Junqueira-de-Azevedo IL. The transcriptome recipe for the venom cocktail of Tityus bahiensis scorpion. Toxicon. 95:52-61 (2015).
  • Drewes CC, Dias RY, Branco VG, Cavalcante MF, Souza JG, Abdalla DS, Chudzinski-Tavassi AM, Farsky SH. Post-transcriptional control of Amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endotelial cells. Toxicon 101:1-10 (2015).
  • Ferreira AK, Tavares MT, Pasqualoto KF, de Azevedo RA, Teixeira SF, Ferreira- Junior WA, Bertin AM, de-Sá-Junior PL, Barbuto JA, Figueiredo CR, Cury Y, Damião MC, Parise-Filho R. RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model. Tumour Biol. 36(9):7251-67 (2015).
  • Fonseca A, Gubitoso MD, Reis MS, Sandro José de Souza SJ, Barrera J. A new approach for identification of cancer-related pathways using protein networks and genomic data. Cancer Informatics, 14 (Suppl 5), 139 (2015).
  • Freitas-de-Sousa LA, Amazonas DR, Sousa LF, Sant’Anna SS, Nishiyama MY Jr, Serrano SM, Junqueira-de-Azevedo IL, Chalkidis HM, Moura-da-Silva AM, Mourão RH. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie 118:60-70 (2015).
  • Gross ER, Zambelli VO, Ferreira JC, Small B, Chen CH. Mochly-Rosen, D. A personalized medicine approach for Asian-Americans with the aldehyde dehydrogenase 2*2 variant. Annual Review of Pharmacology and Toxicology 55: 107-27 (2015).
  • Hui Wen F, Monteiro WM, Moura da Silva AM, Tambourgi DV, Mendonça da Silva I, Sampaio VS, dos Santos MC, Sachett J, Ferreira LC, Kalil J, Lacerda M. Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis. 9(5): e0003701 (2015).
  • Iqbal A, Goldfeder MB, Marques-Porto R, Asif H, Souza JG, Faria F, Chudzinski-Tavassi AM. Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. Sci Rep. 3;7(1):1431 (2017).
  • Jared C.; Mailho-Fontana PL; Antoniazzi MM; Mendes VA; Barbaro KC; Rodrigues MT; Brodie ED. Venomous Frogs Use Heads as Weapons. Current Biology, v. 25, p. 1-5, (2015).
  • Junqueira-de-Azevedo IL, Bastos CM, Ho PL, Luna MS, Yamanouye N, Casewell NR Venom-Related Transcripts from Bothrops jararaca Tissues Provide Novel Molecular Insights into the Production and Evolution of Snake Venom. Mol Biol Evol 32(3):754-66 (2015).
  • Kimura LF, Prezotto-Neto JP, Távora BC, Faquim-Mauro EL, Pereira NA, Antoniazzi MM, Jared SG, Teixeira CF, Santoro ML, Barbaro KC. Mast cells and histamine play na important role in edema and leukocyte recruitment induced by Potamotrygon motoro stingray venom in mice. Toxicon. Sep; 103:65-73 (2015).
  • Kodama RT, Cajado-Carvalho D, Kuniyoshi AK, Kitano ES, Tashima AK, Barna BF, Takakura AC, Serrano SM, Dias-Da-Silva W, Tambourgi DV, Portaro FV. New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms. Biochim Biophys Acta – General Subjects 1850(6):1180-7 (2015).
  • Machado RJ, Junior LG, Monteiro NK, Silva-Júnior AA, Portaro FC, Barbosa EG, Braga VA, Fernandes-Pedrosa MF. Homology modeling, vasorelaxant and bradykininpotentiating activities of a novel hypotensin found in the scorpion venom from Tityus stigmurus. Toxicon Jul; 101:11-8 (2015).
  • Megale AAA, Ferreira Jr MJ, Rangel LBA, Diz MDPE, Mano MS, Hoff PMG, Lopes PH, Arai RJ, Dias da Silva W. Novel Immunogenic Epitopes in the NaPi-IIb Protein: Production of Monospecific Antibodies Using Synthetic Peptides Outlined on Isoform Specific Regions of the Type IIb Sodium-Dependent Phosphate Transporter (NaPi-IIb). Journal of Cancer Therapy 07(02):129-151 (2015).
  • Nishijima CM, Delella FK, Rodrigues CM, Rinaldo D, Lopes-Ferreira M, da Rocha LR, Vilegas W, Felisbino SL, Hiruma-Lima CA The anti-Inflammatory effects of the methanolic extract and fractions from Davilla elliptica St. Hil. (Dilleniaceae) on Bothrops jararaca envenomation. Int J. Mol. Sciences 16(6):12454-12466 (2015).
  • Paixão-Cavalcante D, Kuniyoshi AK, Portaro FC, da Silva WD, Tambourgi DV. African adders: partial characterization of snake venoms from three Bitis species of medical importance and their neutralization by experimental equine antivenoms. PLoS Negl Trop Dis 9(2):e0003419 (2015).
  • Pariona-Llanos R, Pavani RS, Reis M, Noel V, Silber AM, Armelin HA, Cano MI, Elias MC Glyceraldehyde 3-phosphate dehydrogenase-telomere association correlates with redox status in Trypanosoma cruzi. Plos One 10(3): e0120896 (2015).
  • Pedroso A, Matioli SR, Murakami MT, Pidde-Queiroz G, Tambourgi DV. Adaptive evolution in the toxicity of a spider’s venom enzymes. BMC Evol Biol 15:290 (2015).
  • Rodriguez RV, Dorce VA, de Freitas LA, Dorce AL, Lebrun I, Sobral AC, Portaro FC, Kuniyoshi AK, Carvalho DC, Nencioni AL. Intrahippocampal injection of TsTX-I increases the levels of INF-gamma in the cerebral tissue but not the levels of glutamate. Toxicon 103:155-9 (2015).
  • Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant’Anna SS, Barbaro KC, Fernandes W. Ontogenetic variation in biological activities of venoms from hybrids between Bothrops erythromelas and Bothrops neuwiedi snakes. PLoS One 10(12):e0145516 (2015).
  • Sousa LAF, Amazonas DR, Sousa LF, Sant´Anna SS, Nishiyama-Jr MY, Serrano SMT, Junqueira-De-Azevedo ILM, Chalkidis HM, Moura-Da-Silva AM, Mourão RHV. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie (Paris. Print), v. 118, p. 60-70 (2015).
  • Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-1 Presents Potent Anti-Inflammatory Activity. PLoS One 10(8):e0136116. (2015).
  • Villas Boas IM, Pidde-Queiroz G, Magnoli FC, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. A serine protease isolated from the bristles of the Amazonic caterpillar, Premolis semirufa, is a potent complement system activator. PLoS One 10(3):e0118615 (2015).
  • Wen FH, Monteiro WM, Moura da Silva AM, Tambourgi DV, da Silva IM, Sampaio VS, dos Santos MC, Sachett J, Ferreira LCL, Kalil J, Lacerda M. Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis 9(5): e0003701 (2015).
  • Zambelli VO, Chen CH, Gross ER. Reactive aldehydes: an initial path to develop precision medicine for pain control. Ann Transl Med 3(17):258 (2015).
  • Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM, Overall CM. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. J Proteomics 113:260-7 (2015).

2014

  • Andrade GR, New RR, Sant’Anna OA, Williams NA, Alves RC, Pimenta DC, Vigerelli H, Melo BS, Rocha LB, Piazza RM, Mendonça-Previato L, Domingos MO. A universal polysaccharide conjugated vaccine against O111 E. coli. Hum Vaccin Immunother. 2014; 10(10):2864-74.
  • Arantes-Costa FM, Grund LZ, Martins MA, Lima C Airborne pollutant ROFA enhances the allergic airway inflammation through direct modulation of dendritic cells in an uptake-dependent mechanism. Int. Immunopharmacology 22: 9-20 (2014).
  • Asega AF, Oliveira AK, Menezes MC, Neves-Ferreira AG, Serrano SM.Interaction of Bothrops jararaca venom metalloproteinases with protein inhibitors. Toxicon. 2014 Mar; 80:1-8.
  • Baldon EJ, Marengo EB, De Franco M, Starobinas N, Bueno V, Sant’Anna AO. Mycobacterium leprae Hsp65 administration reduces the lifespan of aged high antibody producer mice. Immunity & Ageing. 2014;11:6-16.
  • Bernardoni JL, Sousa LF, Wermelinger LS, Lopes AS, Prezoto BC, Serrano SM, Zingali RB, Moura-da-Silva AM. Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation. PLoS One 9(10):e109651 (2014).
  • Bitencourt MAO, Lima, MCJS, Torres-Rêgo M, Fernandes JM, Silva-Junior AA, Tambourgi DV, Zucolotto SM, Fernandes-Pedrosa MF. Neutralizing Effects of Mimosa tenuiflora Extracts against Inflammation Caused by Tityus serrulatus Scorpion Venom. BioMed Research International. 2014;1-8.
  • Brum FL, Catta-Preta CM, de Souza W, Schenkman S, Elias MC, Motta MC. Structural characterization of the cell division cycle in Strigomonas culicis, an endosymbiont-bearing trypanosomatid. Microsc Microanal. 2014Feb;20(1):228-37.
  • Bueno V, Sant’Anna OA, Lord JM. Ageing and myeloid-derived suppressor cells: possible involvement in immunosenescence and age-related disease. Age (Dordr). 2014; 36(6):9729.
  • Cajado Carvalho D, Kuniyoshi AK, Kodama RT, Oliveira AK, Serrano SM, Tambourgi DV, Portaro FV. Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms. Toxicol Sci 142(2):418-26 (2014).
  • Calderano SG, Godoy PDM, Soares DR, Sant’Anna OA, Schenkman S, Elias MC. ORC1/CDC6 and MCM7 distinct associate with chromatin through Trypanosoma cruzi life cycle. Mol Biochem Parasitol. 2014; 193:110-113.
  • Castilho DG, Chaves AF, Xander P, Zelanis A, Kitano ES, Serrano SM, Tashima AK, Batista WL. Exploring potential virulence regulators in paracoccidioides brasiliensis isolates of varying virulence through quantitative proteomics. J Proteome Res 13(10):4259-71 (2014).
  • Chudzinski-Tavassi AM, Carvalho LCC, Alvarez-Flores MP, Andrade SA.Exogenous procoagulant factors as therapeutic and biotechnological tools. J Blood Disorders Transf. 2014 ; 5:209.
  • de Araujo, Christiane B.; Russo, Lilian C.; Castro, Leandro M.; et al.A Novel Intracellular Peptide Derived from G(1)/S Cyclin D2 Induces Cell Death. Journal of Biological Chemistry Volume: 289 Issue: 24 Pages: 16711-16726 Published: JUN 13 2014
  • Ferreira MJ, Lima C, Lopes-Ferreira M. Anti-inflammatory effect of Natterins, the major toxins from the Thalassophryne nattereri fish venom is dependent on TLR4/MyD88/PI3K signaling pathway. Toxicon (Oxford). 2014;87:54-67.
  • Herrera M, Paiva OK, Pagotto AH, Segura A, Serrano SM, Vargas M, Villalta M, Jensen SD, León G, Williams DJ, Gutiérrez JM. Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia. Am J Trop Med Hyg 91(5):887-94 (2014).
  • Lima MC, Bitencourt MA, Furtado AA, Oliveira Rocha HA, Oliveira RM, Silva Júnior AA, Tabosa do Egito ES, Tambourgi DV, Zucolotto SM, Fernandes Pedrosa MD.Ipomoea asarifolia neutralizes inflammation induced by Tityus serrulatus scorpion venom. J Ethnopharmacol. 2014 Apr 2. pii: S0378 8741(14)00250-5.
  • Lopes-Ferreira M, Gomes EM, Bruni FM, Ferreira MJ, Charvet P, Lima C. First report of interruption of mast cell degranulation and endothelial cells activation by anti-inflammatory drugs controlling the acute response provoked by Pseudoplatystoma fasciatum fish venom. Toxicon 90: 237-248 (2014).
  • Lopes-Ferreira M, Ramos AD, Martins IA, Lima C, Conceição K, Haddad Jr V. Clinical manifestations and experimental studies on the spine extract of the toadfish Porichthys porosissimus. Toxicon (Oxford). 2014;86:28-39.
  • Lopes-Ferreira, Monica; Grund, Lidiane Zito; Lima, Carla. Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system. Journal of Venomous Animals and Toxins including Tropical Diseases Volume: 20 Pages: 1-12 Published: 2014-09
  • Machado, FC. Zambelli VO. Fernandes, ACO. Heimann, AS. Cury, Y. Picolo, G. British. Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine. Journal of Pharmacology 171(4):961-72 (2014).
  • Mariano-Neto F, Matos JR, Cides Da Silva LC, Carvalho LV, Scaramuzzi K, Sant’anna OA, Oliveira CP, Fantini MCA. Physical properties of ordered mesoporous SBA-15 silica as immunological adjuvant. J. Phys. D: Appl. Phys. 47: 425402-425411 (2014).
  • Neves ALC, Chagas AAA, Bizerra AF. Percepção do público de um museu de ciências acerca da experimentação animal [Perception of the audience on animal experimentation in a Science museum]. Revista de Ensino de Biologia da Associação Brasileira de Ensino de Biologia (SBEnBio), 7:445-455 (2014)
  • Pacheco MT, Berra CM, Morais KL et al. Dynein function and protein clearance changes in tumor cells induced by a kunitz-type molecule, amblyomin-X. PloS One 9(12), e111907 (2014).
  • Pasqualoto KF, Balan A, Barreto SA, Simons SM, Chudzinski-Tavassi AM.Structural characterization of the cell division cycle in Strigomonas culicis, an endosymbiont-bearing trypanosomatid. Protein Pept Lett. 2014 May;21(5):452-7.
  • Pasqualoto KF, Balan A, Barreto SA, Simons SM, Chudzinski-Tavassi AM. Structural findings and molecular modeling approach of a TFPI-like inhibitor. Protein and peptide letters 21(5), 452-457 (2014).
  • Remuzgo, Cesar; Sampaio, Sandra; Picolo, Gisele; et al.Crotalphine: fluorescent analogues, structural analysis and its effect on co-cultures of peritoneal macrophages and DRG neurons. Faseb Journal Volume: 28 Issue: 1 Published: APR 2014
  • Serrano SM, Oliveira AK, Menezes MC, Zelanis A. The proteinase-rich proteome of Bothrops jararaca venom. Toxin Reviews.2014; 33:1-16.
  • Silva FS, Ramos RN, Almeida DC, Bassi EJ, Gonzales RP, Miyagi SPH, Maranduba CP, Sant’Anna AO, Marques MM, Barbuto JAM, Olsen N, Maranduba CMC. Mesenchymal Stem Cells Derived from Human Exfoliated Deciduous Teeth (SHEDs) Induce Immune Modulatory Profile in Monocyte-Derived Dendritic Cells. Plos One. 2014;9:1-13.
  • Souza Louvain, T., Magnoli, FC, & Dias da Silva, W. 2014. Characterization of hemorrhage-inducung component present in Bitis arietans venom. Africa J. Biotechnology 14:999-1008 (2014).
  • Squaiella-Baptistão CC, Marcelino JR, Ribeiro da Cunha LE, Gutiérrez JM, Tambourgi DV. Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms. Am J Trop Med Hyg. 2014 Mar;90(3):574-84.
  • Tambourgi DV, Fishelson Z. Preface to the special issue for the XXV International Complement Workshop. Mol Immunol. 61(2):55 (2014).
  • Tambourgi DV, van den Berg CW. Animal venoms/toxins and the complement system. Mol Immunol. 2014 Jul 3. pii: S0161-5890(14)00151-5.
  • van den Berg CW, Tambourgi DV, Clark HW, Hoong SJ, Spiller OB, McGreal EP. Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the c5a receptor. J Immunol. 2014 Feb 15;192(4):1787-95.
  • Wlian L, Carrijo-Carvalho LC, Andrade AS, Lorenco SV, Rodrigues CJ, Maria DA, Chudzinski-Tavassi AM. Wound Healing Effects of a Lipocalin-Derived Peptide. J Clin Toxicol. 2014; 4:187.
  • Yamashiro ET, Oliveira AK, Kitano ES, Menezes MC, Junqueira-de-Azevedo IL, Paes Leme AF, Serrano SM. Proteoforms of the platelet-aggregating enzyme PA-BJ, a serine proteinase from Bothrops jararaca venom. Biochim Biophys Acta – Proteins and Proteomics 1844(12):2068-2076 (2014).
  • Zambelli VO, Fernandes AC, Gutierrez VP, Ferreira JC, Parada CA, Mochly-Rosen D, Cury Y. Peripheral sensitization increases opioid receptor expression and activation by crotalphine in rats. PLoS One. 2014 Mar 4;9(3):e90576.
  • Zambelli VO, Gross ER, Chen CH, Gutierrez VP, Cury Y, Mochly-Rosen D. Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain. Science Translational Medicine 6(251): 251ra118 (2014).
  • Zuma AA, Mendes IC, Reignault de Souza LC, Elias MC, de Souza W, Machado CR, Motta MC. How Trypanosoma cruzi handles cell cycle arrest promoted by camptothecin, a topoisomerase I inhibitor. Mol Biochem Parasitol. 2014 Feb 11. pii: S0166-6851(14)00017-6.
  • Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant’Anna SS, Barbaro KC, Fernandes W. Ontogenetic variation in biological activities of venoms from hybrids between Bothrops erythromelas and Bothrops neuwiedi snakes. PLoS One 10(12):e0145516 (2015).
  • Sousa LAF, Amazonas DR, Sousa LF, Sant´Anna SS, Nishiyama-Jr MY, Serrano SMT, Junqueira-De-Azevedo ILM, Chalkidis HM, Moura-Da-Silva AM, Mourão RHV. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie (Paris. Print), v. 118, p. 60-70 (2015).
  • Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-1 Presents Potent Anti-Inflammatory Activity. PLoS One 10(8):e0136116. (2015).
  • Villas Boas IM, Pidde-Queiroz G, Magnoli FC, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. A serine protease isolated from the bristles of the Amazonic caterpillar, Premolis semirufa, is a potent complement system activator. PLoS One 10(3):e0118615 (2015).
  • Wen FH, Monteiro WM, Moura da Silva AM, Tambourgi DV, da Silva IM, Sampaio VS, dos Santos MC, Sachett J, Ferreira LCL, Kalil J, Lacerda M. Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis 9(5): e0003701 (2015).
  • Zambelli VO, Chen CH, Gross ER. Reactive aldehydes: an initial path to develop precision medicine for pain control. Ann Transl Med 3(17):258 (2015).
  • Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM, Overall CM. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. J Proteomics 113:260-7 (2015).

2013

  • Carvalho DC, Duzzi B, Kuniyoshi AK, Fioramonte M, Gozzo FC, Melo RL, Tambourgi DV, Rioli V, Portaro FC. Insights into scorpion venom peptides: alternative processing of β-KTx propeptide from Tityus serrulatus venom results in a new naturally occurring thimet oligopeptidase inhibitor. Peptides. 2013 Feb; 40:30-3.
  • da Silva MC, Lasunskaia EB, Dias da Silva W. Repeated inoculations of Mycobacterium bovis Bacille Calmette- Guérin (BCG) are needed to induce a strong humoral immune response against antigens expressed by the bacteria*. Open Journal of Immunology. 2013 ;3:71-81.
  • Da Silva, M.S.; Monteiro JP, Nunes VS, Vasconcelos EJ, Perez AM, Freitas-Junior L de H, Elias MC, Cano MI. Anucleus and kinetoplast segregation during cell cycle. PloS One. 2013 ;8:e81397.
  • Dias GS, Kitano ES, Pagotto AH, Sant’anna SS, Rocha MM, Zelanis A, Serrano SM. Individual variability in the venom proteome of juvenile Bothrops jararaca specimens.J Proteome Res. 2013 Oct 4;12(10):4585-98.
  • Fernandes de Oliveira LM, Ullah A, Masood R, Zelanis A, Spencer PJ, Serrano SM, Arni RK. Rapid purification of serine proteinases from Bothrops alternatus and Bothrops moojeni venoms. Toxicon. 2013 Dec 15; 76:282-90.
  • Frauches TS, Petretski JH, Arnholdt AC, Lasunskaia EB, de Carvalho EC, Kipnis TL, da Silva WD, Kanashiro MM. Bothropic antivenom based on monoclonal antibodies, is it possible? Toxicon. 2013 Sep; 71:49-56.
  • Grund, L.Z.; Lopes-Ferreira M.; Lima, C. The hierarchical process of differentiation of long-lived antibodysecreting cells is dependent on integrated signals derived from antigen and IL-17A. PLoS One. 2013 Sep 18;8(9):e74566.
  • Guidolin FR, Tambourgi DV, Guidolin R, Marcelino JR, Okamoto CK, Magnoli FC, Queiroz GP, Dias da Silva W.Characterization of anti-crotalic antibodies. Toxicon. 2013 May; 66:7-17.
  • Kitano ES, Garcia TC, Menezes MC, Tashima AK, Zelanis A, Serrano SM. Cotiarinase is a novel prothrombin activator from the venom of Bothrops cotiara. Biochimie. 2013 Aug;95(8):1655-9.
  • Komegae EM, Grund LZ, Lopes-Ferreira M, Lima C. Plos One. TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells. 2013;8:e71185.
  • Komegae EN, Grund LZ, Lopes-Ferreira M, Lima C. The longevity of Th2 humoral response induced by proteases natterins requires the participation of long-lasting innate-Like B cells and plasma cells in spleen. PLoS One. 2013 Jun 28;8(6):e67135.
  • LARA PG, Prudente MFS, Dias NMC, Tambourgi DV, Lino-Junior RS, Spadafora-Ferreira M, Carvalhaes MS.Analysis of Spleen Cells in Susceptible and Resistant Mice with Experimental Lagochilascariosis. ISRN Parasitology. 2013;1-8.
  • Lopes PH, Bertani R, Gonçalves-de-Andrade RM, Nagahama RH, van den Berg CW, Tambourgi DV. Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. PLoS Negl Trop Dis. 2013 Aug 22;7(8):e2394.
  • Mafra CS, Carrijo-Carvalho LC, Chudzinski-Tavassi AM, Taguchi FM, Foronda AS, Carvalho FR, de Freitas D. Antimicrobial action of biguanides on the viability of Acanthamoeba cysts and assessment of cell toxicity. Invest Ophthalmol Vis Sci. 2013 Sep 27;54(9):6363-72.
  • Maria DA, de Souza JG, Morais KL, Berra CM, Zampolli H de C, Demasi M, Simons SM, de Freitas Saito R, Chammas R, Chudzinski-Tavassi AM.A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production. Invest New Drugs. 2013 Jun;31(3):493-505.
  • Mesquita Pasqualoto KF, Carrijo-Carvalho LC, Chudzinski-Tavassi AM. Rational development of novel leads from animal secretion based on coagulation and cell targets: 1. In silico analysis to explore a peptide derivative as lipocalins’ signature. Toxicon. 2013 Jul; 69:200-10.
  • Morais KL, Mesquita Pasqualoto KF, Pacheco MTF, Berra CM, Alvarez-Flores MP, Chudzinski-Tavassi AM. Rational development of a novel TFPI-like inhibitor from Amblyomma cajennense tick. Toxin Reviews. 2013 ;33:1-
  • Morais-Zani K, Nunes FPB, Silva BJ, Ferreira MJ, Grego KF, Lopes-Ferreira M, Tanaka AS, Tanaka-Azevedo AM.The anti-inflammatory action of Bothrops jararaca snake antithrombin on acute inflammation induced by carrageenan in mice. Inflamm. Res. 2013 ;62:733-742.
  • Motta MC, Martins AC, de Souza SS, Catta-Preta CM, Silva R, Klein CC, de Almeida LG, de Lima Cunha O, Ciapina LP, Brocchi M, Colabardini AC, de Araujo Lima B, Machado CR, de Almeida Soares CM, Probst CM, de Menezes CB, Thompson CE, Bartholomeu DC, Gradia DF, Pavoni DP, Grisard EC, Fantinatti-Garboggini F, Marchini FK, Rodrigues-Luiz GF, Wagner G, Goldman GH, Fietto JL, Elias MC, Goldman MH, Sagot MF, Pereira M, Stoco PH, de Mendonça-Neto RP, Teixeira SM, Maciel TE, de Oliveira Mendes TA, Ürményi TP, de Souza W, Schenkman S, de Vasconcelos AT. Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae Family. PLoS One. 2013;8(4):e60209.
  • Paes LS, Suárez Mantilla B, Zimbres FM, Pral EM, Diogo de Melo P, Tahara EB, Kowaltowski AJ, Elias MC, Silber AM.Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi. PLoS One. 2013 Jul 22;8(7):e69419.
  • Paixao-Cavalcante, D.; Dias da Silva, W.; Vilarinho Tambourgi, D. Envenomation by African adders (Bitis ssp.) induces complement activation. Molecular Immunology Volume: 56 Issue: 3 Pages: 259-260 Published: DEC 15 2013
  • Pidde-Queiroz G, Magnoli FC, Portaro FC, Serrano SM, Lopes AS, Paes Leme AF, van den Berg CW, Tambourgi DV. P-I snake venom metalloproteinase is able to activate the complemente system by direct cleavage of central components of the cascade. PLoS Negl Trop Dis. 2013;7(10):e2519.
  • Salotti J, Dias MH, Koga MM, Armelin HA. Fibroblast growth factor 2 causes G2/M cell cycle arrest in ras-driven tumor cells through a Src-dependent pathway. PLoS One. 2013 Aug 26;8(8):e72582.
  • Serrano SM. The long road of research on snake venom serine proteinases. Toxicon. 2013 Feb; 62:19-26
  • Venancio EJ, Portaro FC, Kuniyoshi AK, Carvalho DC, Pidde-Queiroz G, Tambourgi DV. Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms. Toxicon. 2013 Jul;69:180-90.
  • Ventura JS, Faria F, Batista IF, Simons SM, Oliveira DG, Morais KL, Chudzinski-Tavassi AM. A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis. Biomed Pharmacother. 2013 Apr;67(3):192-6.
  • Vieira ML, Alvarez-Flores MP, Kirchgatter K, Romero EC, Alves IJ, de Morais ZM, Vasconcellos SA, Chudzinski-Tavassi AM, Nascimento AL. Interaction of Leptospira interrogans with human proteolytic systems enhances dissemination through endothelial cells and protease levels. Infect Immun. May;81(5):1764-74 (2013).
  • Villas-Boas IM, Gonçalves-de-Andrade RM, Squaiella-Baptistão CC, Sant’Anna OA, Tambourgi DV. Characterization of phenotypes of immune cells and cytokines associated with chronic exposure to Premolis semirufa caterpillar bristles extract. PLoS One. 2013 Sep 4;8(9):e71938.
  • ZM, Vasconcellos SA, Chudzinski-Tavassi AM, Nascimento AL. Interaction of Leptospira interrogans with human proteolytic systems enhances dissemination through endothelial cells and protease levels. Infect Immun. 2013 May;81(5):1764-74.

Pesquisadores devem fazer referência ao apoio da FAPESP de acordo com o seguinte modelo:
“Processo 2013/07467-1, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)”

Publications

Papers published
by CeTICS
from 2013 to 2019

Integrated

Researches developed by groups of investigators within CeTICS

Highlights

Research examples that resulted
in products, applications and patents
or will possibly become a product.