Artigos

2022

  1. Alcantara LCJ, Nogueira E, Shuab G, Tosta S, Fristch H, Pimentel V, Souza-Neto JA, Coutinho LL, Fukumasu H, Sampaio SC, Elias MC, Kashima S, Slavov SN, Ciccozzi M, Cella E, Lourenco J, Fonseca V, Giovanetti M. SARS-CoV-2 epidemic in Brazil: how the displacement of variants has driven distinct epidemic waves. Virus Res. Jul 2;315:198785. Epub 2022 Apr 21.PMID: 35461905 (2022).
  2. Alvarez AM, Alvarez-Flores MP, DeOcesano-Pereira C, Goldfeder MB, Chudzinski-Tavassi AM, Moreira V, Teixeira C. Losac and Lopap Recombinant Proteins from Lonomia obliqua Bristles Positively Modulate the Myoblast Proliferation Process. Front Mol Biosci. Jun 29;9:904737 (2022).
  3. Andrade SA, Batalha-Carvalho JV, Curi R, Wen FH, Covas DT, Chudzinski-Tavassi AM, Moro AM. Equine Anti-SARS-CoV-2 Serum (ECIG) Binds to Mutated RBDs and N Proteins of Variants of Concern and Inhibits the Binding of RBDs to ACE-2 Receptor. Front Immunol. Jul 11;13:871874 (2022).
  4. Botosso VF, Jorge SAC, Astray RM, de Sá Guimarães AM, Mathor MB, de Carneiro PDS, Durigon EL, Covas D, de Oliveira DBL, das Neves Oliveira R, Maria DA, Eto SF, Gallina NMF, Pidde G, Squaiella-Baptistão CC, Silva DT, Villas-Boas IM, Fernandes DC, Auada AVV, Banari AC, de Souza Filho AF, Bianconi C, de Agostini Utescher CL, Oliveira DCA, Mariano DOC, Barbosa FF, Rondon G, Kapronezai J, da Silva JG, Goldfeder MB, Comone P, Junior REC, Pereira TTS, Wen FH, Tambourgi DV, Chudzinski-Tavassi AM. Anti-SARS-CoV-2 equine F (Ab’)2 immunoglobulin as a possible therapy for COVID-19. Sci Rep. Mar 10;12(1):3890 (2022).
  5. Brás-Costa C, Chaves AFA, Cajado-Carvalho D, da Silva Pires D, Andrade-Silva D, Serrano SMT. Profilings of subproteomes of lectin-binding proteins of nine Bothrops venoms reveal variability driven by different glycan types.Biochim Biophys Acta Proteins Proteom. Jul 1;1870(7):140795 (2022).
  6. Brás-Costa, C, Chaves, AFA, Trevisan-Silva D, Menezes MC, Rocha MMT, Cajado-Carvalho D, Andrade-Silva D, Serrano SMT. Sialic acid-containing glycans play a role in the activity of snake venom proteases. Biochimie, in press. (2022).
  7. Brzoskowski dos Santos G; Silva E, Kitano ES, Battistella ME, Monteiro KM, Lima JC, Ferreira HB, Serrano SMT, Zaha A. Proteomic profiling of hydatid fluid from pulmonary cystic echinococcosis. Parasites & Vectors. Mar 21;15(1):99 (2022).
  8. Caetano BL, Domingos MO, da Silva MA, da Silva JCA, Polatto JM, Montoni F, Iwai LK, Pimenta DC, Vigerelli H, Vieira PCG, Ruiz RC, Patané JS, Piazza RMF. In Silico Prediction and Design of Uropathogenic Escherichia coli Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin. Microorganisms. Jan 14;10(1):172 (2022).
  9. Charlie-Silva I, Feitosa NM, Pontes LG, Fernandes BH, Nóbrega RH, Gomes JMM, Prata MNL, Ferraris FK, Melo DC, Conde G, Rodrigues LF, Aracati MF, Corrêa-Junior JD, Manrique WG, Superio J, Garcez AS, Conceição K, Yoshimura TM, Núñez SC, Eto SF, Fernandes DC, Freitas AZ, Ribeiro MS, Nedoluzhko A, Lopes-Ferreira M, Borra RC, Barcellos LJG, Perez AC, Malafaia G, Cunha TM, Belo MAA, Galindo-Villegas J. Plasma proteome responses in zebrafish following λ-carrageenan-Induced inflammation are mediated by PMN leukocytes and correlate highly with their human counterparts. Front Immunol. Sep 29;13:1019201 (2022).
  10. Courrol DDS, da Silva CCF, Prado LG, Chura-Chambi RM, Morganti L, de Souza GO, Heinemann MB, Isaac L, Conte FP, Portaro FCV, Rodrigues-da-Silva RN, Barbosa AS. Leptolysin, a Leptospira secreted metalloprotease of the pappalysin family with broad-spectrum activity. Front Cell Infect Microbiol. Aug 23;12:966370 (2022).
  11. de Andrade SA, de Souza DA, Torres AL, de Lima CFG, Ebram MC, Celano RMG, Schattner M, Chudzinski-Tavassi AM. Pathophysiology of COVID-19: Critical Role of Hemostasis. Front Cell Infect Microbiol. Jun 3;12:896972 (2022).
  12. De Sá Schiavo GM, Da Silva RNB, Carreira ACO, Junior MYN, Fratini P, Ferreira CR, Miglino MA. Proteomic profile of extracellular matrix from native and decellularized chorionic canine placenta. Journal of Proteomics, v. 256, p. 104497 (2022).
  13. Dias da Silva W, De Andrade SA, Megale AAA, Souza DA, Sant’Anna OA, Magnoli FC, Guidolin FR, Godoi KS, Saladini LY, Spencer OS, Portaro FCV. Antibodies as Snakebite Antivenoms: Past and Future. Toxins. 14, 606 (2022).
  14. Disner GR, Carla Lima, Monica Lopes-Ferreira. Ecotoxicol. Environ. Contam. It takes a school [of fish] to avoid an environmental collapse: Zebrafish as an outstanding alternative animal model in chemical toxicity screening.,v. 17, n. 1, 2022, 67-69 (2022).
  15. Gilson Sena IF, Fernandes LL, Lorandi LL, Santana TV, Cintra L, Lima IF, Iwai LK, Kramer JM, Birbrair A, Heller D. Identification of early biomarkers in saliva in genetically engineered mouse model C(3)1-TAg of breast cancer. Sci Rep. Jul 7;12(1):11544 (2022).
  16. Giovanetti M, Slavov SN, Fonseca V, Wilkinson E, Tegally H, Patané JSL, Viala VL, San EJ, Rodrigues ES, Santos EV, Aburjaile F, Xavier J, Fritsch H, Adelino TER, Pereira F, Leal A, Iani FCM, de Carvalho Pereira G, Vazquez C, Sanabria GME, Oliveira EC, Demarchi L, Croda J, Dos Santos Bezerra R, Paola Oliveira de Lima L, Martins AJ, Renata Dos Santos Barros C, Marqueze EC, de Souza Todao Bernardino J, Moretti DB, Brassaloti RA, de Lello Rocha Campos Cassano R, Mariani PDSC, Kitajima JP, Santos B, Proto-Siqueira R, Cantarelli VV, Tosta S, Nardy VB, Reboredo de Oliveira da Silva L, Gómez MKA, Lima JG, Ribeiro AA, Guimarães NR, Watanabe LT, Barbosa Da Silva L, da Silva Ferreira R, da Penha MPF, Ortega MJ, de la Fuente AG, Villalba S, Torales J, Gamarra ML, Aquino C, Figueredo GPM, Fava WS, Motta-Castro ARC, Venturini J, do Vale Leone de Oliveira SM, Gonçalves CCM, do Carmo Debur Rossa M, Becker GN, Giacomini MP, Marques NQ, Riediger IN, Raboni S, Mattoso G, Cataneo AD, Zanluca C, Duarte Dos Santos CN, Assato PA, Allan da Silva da Costa F, Poleti MD, Lesbon JCC, Mattos EC, Banho CA, Sacchetto L, Moraes MM, Grotto RMT, Souza-Neto JA, Nogueira ML, Fukumasu H, Coutinho LL, Calado RT, Neto RM, Bispo de Filippis AM, Venancio da Cunha R, Freitas C, Peterka CRL, de Fátima Rangel Fernandes C, Navegantes W, do Carmo Said RF, Campelo de A E Melo CF, Almiron M, Lourenço J, de Oliveira T, Holmes EC, Haddad R, Sampaio SC, Elias MC, Kashima S, Junior de Alcantara LC, Covas DT. Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil. Nat Microbiol. Sep;7(9):1490-1500 Epub 2022 Aug 18.PMID: 35982313 (2022).
  17. Leonel TB, Gabrili JJM, Squaiella-Baptistão CC, Woodruff TM, Lambris JD, Tambourgi DV. Bothrops jararaca Snake Venom Inflammation Induced in Human Whole Blood: Role of the Complement System. Front Immunol. Jun 2; 13: 885223 (2022).
  18. Lima ARJ, Ribeiro G, Viala VL, de Lima LPO, Martins AJ, Barros CRDS, Marqueze EC, Bernardino JST, Moretti DB, Rodrigues ES, Santos EV, Brassaloti RA, Cassano RLRC, Mariani PDSC, Clemente LG, Assato PA, Costa FADSD, Poleti MD, Lesbon JCC, Mattos EC, Banho CA, Sacchetto L, Moraes MM, Palmieri M, Martininghi M, Caldeira LAV, Silva FEVD, Grotto RMT, Souza-Neto JA, Giovanetti M, Junior Alcantara LC, Nogueira ML, Fukumasu H, Coutinho LL, Kashima S, Neto RM, Covas DT, Slavov SN, Sampaio SC, Elias MC. SARS-COV-2 genomic monitoring in the state of São Paulo unveils two emerging AY.43 sublineages. J Med Virol. Jul;94(7):3394-3398 (2022).
  19. Lima ARJ, Silva HGS, Poubel S, Rosón JN, de Lima LPO, Costa-Silva HM, Gonçalves CS, Galante PAF, Holetz F, Motta MCM, Silber AM, Elias MC, da Cunha JPC. Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. Epigenetics Chromatin. Jun 1;15(1):22 (2022).
  20. Lima C, Andrade-Barros AI, Bernardo JTG, Balogh E, Quesniaux VF, Ryffel B, Lopes-Ferreira M. Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway. Int J Mol Sci. Mar 25;23(7):3600 (2022).
  21. Lima C, Eto SF, Lopes-Ferreira M. Pharmaceuticals (Basel). Shedding Light on the Drug-Target Prediction of the Anti-Inflammatory Peptide TnP with Bioinformatics Tools. Aug 12;15(8):994 (2022).
  22. Lima C, Maleski ALA, Bernardo JTG, Zelli VC, Komegae EN, Lopes-Ferreira M. TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model. Front Immunol. Mar 24;13:857692 (2022).
  23. Lima SMRR, Gamberini MT, Rodrigues DS, Junior PIS & Torres KAdM. Antimicrobial And Synergistic Activity of The Drug Association of Allium sativum And Antibiotics Against Group B Streptococcus. Scientific Reports – Preprint – https://doi.org/10.21203/rs.3.rs-1149854/v1 (2022).
  24. Lima C, Falcão MAP, Rosa JGS, Disner GR, Lopes-Ferreira M. Pesticides and Their Impairing Effects on Epithelial Barrier Integrity, Dysbiosis, Disruption of the AhR Signaling Pathway and Development of Immune-Mediated Inflammatory Diseases. Int J Mol Sci. Oct 17;23(20):12402 (2022).
  25. Lobba ARM, Alvarez-Flores MP, Fessel MR, Buri MV, Oliveira DS, Gomes RN, Cunegundes PS, DeOcesano-Pereira C, Cinel VD, Chudzinski-Tavassi AM. A Kunitz-type inhibitor from tick salivary glands: A promising novel antitumor drug candidate. Front Mol Biosci. Aug 16;9:936107 (2022).
  26. Lopes-Ferreira M, Maleski ALA, Balan-Lima L, Bernardo JTG, Hipolito LM, Seni-Silva AC, Batista-Filho J, Falcao MAP, Lima C. Impact of Pesticides on Human Health in the Last Six Years in Brazil. Int J Environ Res Public Health. Mar 9;19(6):3198 (2022).
  27. Lopes-Ferreira M, Sosa-Rosales I, Silva Jr. PI, Conceição K, Maleski ALA, Balan-Lima L, Disner GR, Loma C. Molecular Characterization and Functional Analysis of the Nattectin-like Toxin from the Venomous Fish Thalassophryne maculosa. Toxins (Basel). Dec 21;14(1):2-18 (2022).
  28. Maleski ALA, Rosa JGS, Bernardo JTG, Astray RM, Walker CIB, Lopes-Ferreira M, Lima C. Recapitulation of Retinal Damage in Zebrafish Larvae Infected with Zika Virus. Cells. Apr 26;11(9):1457(2022).
  29. Moraes L, Trentini MM, Fousteris D, Eto SF, Chudzinski-Tavassi AM, Leite LCC, Kanno AI. CRISPR/Cas9 Approach to Generate an Auxotrophic BCG Strain for Unmarked Expression of LTAK63 Adjuvant: A Tuberculosis Vaccine Candidate. Front Immunol. Mar 30;13:867195 (2022).
  30. Munhoz DD, Silva JCA, Freitas NC, Iwai LK, Aires KA, Ozaki CY, Souza CS, Rocha LB, Silva MA, Henrique IM, Elias WP, Carvalho E, Morganti L, Chura-Chambi RM, Piazza RMF.Recombinant PilS: Cloning, Expression and Biochemical Characterization of a Pil-Fimbriae Subunit. Microorganisms. Jun 7;10(6):1174 (2022).
  31. Norton RS, Tambourgi DV. Toxicon and Toxicon: X – 2022 and beyond. Toxicon X. Feb 7;13:100098 (2022).
  32. Norton RS, Tambourgi DV. Toxicon and Toxicon: X – 2022 and beyond. Toxicon. 2022 Feb 7:S0041-0101(22)00037-X (2022).
  33. Pucca MB, Tambourgi DV and Monteiro WM (2022) Editorial: Immune responses and immune mechanisms triggered by snake and scorpion venoms. Front. Immunol. Sept.13;13:988924 (2022).
  34. Rosa JGS, Lima C, Lopes-Ferreira M. Int J Mol Sci. Zebrafish Larvae Behavior Models as a Tool for Drug Screenings and Pre-Clinical Trials: A Review. Jun 14;23(12):6647 (2022).
  35. Roson JN, Vitarelli MO, Costa-Silva HM, Pereira KS, Pires DS, Lopes LS, Cordeiro B, Kraus AJ, Cruz KNT, Calderano SG, Fragoso SP, Siegel TN, Elias MC, da Cunha JPC. H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion. PLoS Pathogensv. 18, p. e1009694 (2022).
  36. Santos WS, Montoni F, Eichler RAS, Arcos SSS, Andreotti DZ, Kisaki CY, Evangelista KB, Calacina HM, Lima IF, Soares MAM, Gren ECK, Carvalho VM, Ferro ES, Nishiyama-Jr MY, Chen Z, Iwai LK. Proteomic analysis reveals rattlesnake venom modulation of proteins associated with cardiac tissue damage in mouse hearts. J Proteomics. Feb 17;258:104530 (2022).
  37. Seni-Silva AC, Maleski ALA, Souza MM, Falcão MAP, Disner GR, Lopes-Ferreira M, Lima C. Natterin-like depletion by CRISPR/Cas9 impairs zebrafish (Danio rerio) embryonic development. BMC Genomics. Feb 12;23(1):123 (2022).
  38. Silva PBD, Silva JRD, Rodrigues MC, Vieira JA, Andrade IA, Nagata T, Santos AS, Silva SWD, Rocha MCOD, Báo SN, Moraes-Vieira PM, Proença-Modena J, Angelim MKC, de Souza GF, Muraro SP, de Barros ALB, de Souza Martins GA, Ribeiro-Dias F, Machado G, Fessel MR, Chudzinski-Tavassi AM, Ronconi CM, Gonçalves D, Curi R, Oliveira ON, Azevedo RB. Detection of SARS-CoV-2 virus via dynamic light scattering using antibody-gold nanoparticle bioconjugates against viral spike protein. Talanta. Jun 1;243:123355 (2022).
  39. Slavov SN, Bezerra RDS, Rodrigues ES, Santos EV, Borges JS, de la Roque DGL, Patané JSL, Lima ARJ, Ribeiro G, Viala VL, de Lima LPO, Martins AJ, Dos Santos Barros CR, Marqueze EC, Bernardino JST, Moretti DB, Brassaloti RA, Cassano RLRC, Mariani PDSC, Kitajima JP, Santos B, Assato PA, da Silva da Costa FA, Poleti MD, Lesbon JCC, Mattos EC, Banho CA, Sacchetto L, Moraes MM, Grotto RMT, Souza-Neto JA, Giovanetti M, de Alcantara LCJ, Nogueira ML, Fukumasu H, Coutinho LL, Calado RT, Neto RM, Covas DT, Coccuzzo Sampaio S, Elias MC, Kashima S. Genomic monitoring of the SARS-CoV-2 B1.1.7 (WHO VOC Alpha) in the Sao Paulo state, Brazil. Virus Res. Jan 15;308:198643. Epub 2021 Nov 27.PMID: 34848213 (2022).
  40. Viala VL, Slavov SN, de Lima LPO, Lima ARJ, Ribeiro G, Martins AJ, Petry B, Banho CA, Barros CRDS, Moncau CT, Moretti DB, de La-Roque DGL, Marqueze EC, Mattos EC, Costa FADSD, Fukumasu H, Bernardino JST, Souza-Neto JA, Lesbon JCC, Kayanoki LP, Bernardo LL, Sacchetto L, Clemente LG, Alcantara LCJ, Coutinho LL, Marques BC, Giovanetti M, Nogueira ML, Poleti MD, Assato PA, Cattony Neto PQ, Cassano RLRC, Neto RM, Grotto RMT, Brassaloti RA, Kashima S, Covas DT, Elias MC, Sampaio SC. The Divergent Pattern of SARS-CoV-2 Variant Predominance and Transmission Dynamics in the Brazilian Island of Ilhabela. Viruses. Jul 5;14(7):1481 (2022).

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2021

  1. Alberto-Silva C, Portaro FCV, Kodama RT, Pantaleão HQ, Rangel M, Nihei KI, Konno K. Novel neuroprotective peptides in the venom of the solitary scoliid wasp Scolia decorata ventralis. J Venom Anim Toxins Incl Trop DisJun 11;27:e20200171 (2021).
  2. Alberto-Silva C, Vieira Portaro FC, Kodama RT, Pantaleão HQ, Inagaki H, Nihei KI, Konno K. Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata. Toxins (Basel). Dec 10;13(12):885 (2021).
  3. Almeida DD, Viala VL, Nachtigall PG, Broe M, Gibbs HL, Serrano SMT, Moura-da-Silva AM, Ho PL, Nishiyama-Jr MY, Junqueira-de-Azevedo ILM. Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca Proc Natl Acad Sci U S A. May 18;118(20):e2015159118 (2021).
  4. Alvarez-Flores MP, Gomes RN, Trevisan-Silva D, Oliveira DS, Batista IFC, Buri MV, Alvarez AM, DeOcesano-Pereira C, de Souza MM, Chudzinski-Tavassi AM. Lonomia obliqua Envenoming and Innovative Research. Toxins (Basel). Nov 23;13(12):832 (2021).
  5. Alves BR, Sutti R, Da Silva Jr PI, Bertani R, Santos-Junior JG, Rocha e Silva TAA and Linardi A. Non-Clinical Evidence Supports Anti-Inflammatories as More Effective Medication than Antihistamines against Tarantula Local Effects Envenomation. BioRxiv-The Preprint Server for Biology, April (2021).
  6. Andrade-Silva D, Nishiyama MY Jr, Stuginski DR, Zelanis A, Serrano SMT. The distinct N-terminomes of Bothrops jararaca newborn and adult venoms. Biochim Biophys Acta Proteins Proteom. 1869(7):140643 (2021).
  7. Andrade-Silva D, Zelanis A, Travaglia-Cardoso SR, Nishiyama MY Jr, Serrano SMT. Venom Profiling of the Insular Species Bothrops alcatraz: Characterization of Proteome, Glycoproteome, and N-Terminome Using Terminal Amine Isotopic Labeling of Substrates. J Proteome Res 20(2):1341-1358 (2021).
  8. Arruda GLM, Vigerelli H, Bufalo MC, Longato GB, Veloso RV, Zambelli VO, Picolo G, Cury Y, Morandini AC, Marques AC, Sciani JM. Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron’s Connection: A Possible Neuroprotector Effect. Biomed Res Int. 2021 Mar 4; 2021:8855248 (2021).
  9. Badari JC, Diaz-Roa A, Rocha MMT, Mendonça RZ and da Silva Junior PI. “Patagonin-CRISP: Antimicrobial Activity and Source of Antimicrobial Molecules in Duvernoy’s Gland”. Frontiers in Pharmacology, Feb. 11(586705):1-11pp (2021).
  10. Bagatelli FM, De Luna Vitorino FN Cunha JPC, Oliveira CC. The ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events. Nucleic Acids Research v. 49, p. 7053-7074, (2021).
  11. Batista-Feilho J, Falcão MAP, Maleski ALA,  Soares  ABS, Balan-Lima L,  Disner  GR, Lima C, Lopes-Ferreira M. Early preclinical screening using zebrafish (Danio rerio) reveals the safety of the candidate anti-inflammatory therapeutic agent TnP. Toxicology Reports, v. 8, p. 13-22 (2021).
  12. Bertholim L, Chaves AFA, Oliveira AK, Menezes MC, Asega AF, Tashima AK, Zelanis A, Serrano SMT. Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins.Toxins (Basel). 13(11):764 (2021).
  13. Bueno TC, Collaço RC, Cardoso BA, Bredariol RF, Escobar ML, Cajado IB, Gracia M, Antunes E, Zambelli VO, Picolo G, Cury Y, Morandini AC, Marques AC, Sciani JM, Rocha T. Neurotoxicity of Olindias sambaquiensis and Chiropsalmus quadrumanus extracts in sympathetic nervous system. Toxicon. Aug;199:127-138 (2021).
  14. Camargo LL, Denadai-Souza A, Yshii LM, Lima C, Teixeira SA, Cerqueira ARA, Gewehr MCF, Fernandes ES, Schenka AA, Muscará MN, Ferro ES, Costa SKP. The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis. Eur J Pharmacol. 890:173636. 2021 Oct 11:173636 (2021).
  15. Cantero PTM, da Silva Jr PI, Negri G, Nascimento RM, Mendonça RZ. Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. bioRxiv – Preprint (2021)
  16. Cararo-Lopes E, Dias MH, da Silva MS, Zeidler JD, Vessoni AT, Reis MS, Boccardo E and Armelin HA. Autophagy buffers Ras-induced genotoxic stress enabling malignant transformation in keratinocytes primed by human Papillomavirus. Cell Death & Disease Feb 18;12(2):194. (2021).
  17. da Silva BS, Díaz-Roa A, Yamane ES, Hayashi MAF & da Silva Junior PI. Doderlin: Isolation and Characterization of a Broad-Spectrum Antimicrobial Peptide from Lactobacillus acidophilus. bioRxiv – Preprint (2021)
  18. Dantas LLB, Dourado MM, Lima NO, Cavaçana N, Nishiyama MY, Souza GM, Carneiro MS, Caldana C, Hotta CT. Field microenvironments regulate crop diel transcript and metabolite rhythms. NEW PHYTOLOGIST, v. 231, p. nph.17650, 2021 (2021).
  19. de Assis RAB, Varani AM, Sagawa CH, Patané JS, Setubal JC, Uceda-Campos G and Dandekar AM. A comparative genomic analysis of Xanthomonas arboricola pv. juglandis strains reveal hallmarks of mobile genetic elements in the adaptation and accelerated evolution of virulence. Genomics. Jun 3;113(4):2513-2525. (2021).
  20. de Freitas BG, Hösch NG, Pereira LM, Barbosa TC, Picolo G, Cury Y, Zambelli VO. PKCζ-Mitogen-Activated Protein Kinase Signaling Mediates Crotalphine-Induced Antinociception. Toxins (Basel). Dec 20;13(12):912 (2021).
  21. De Lucca Caetano LH, Nishiyama-Jr MY, De Carvalho Lins BFT, De Oliveira UC, De Loiola Meirelles Junqueira-De-Azevedo I, Faquim-Mauro EL, Magalhães GS. Recombinant Production and Characterization of a New Toxin from Cryptops iheringi Centipede Venom Revealed by Proteome and Transcriptome Analysis. Toxins, v. 13, p. 858 (2021).
  22. Disner GR, Falcao MAP, Andrade-Barros AI, Leite-Santos NV, Soares ABS, Marcolino-Souza M, Gomes KS, Lima C, Lopes-Ferreira M. The toxic effects of glyphosate, chlorpyrifos, abamectin, and 2,4-D on animal models: a systematic review of Brazilian studies. Integr Environ Assess Manag. May;17(3):507-520 (2021).
  23. Disner GR, Falcão MAP, Lima C, Lopes-Ferreira M. In silico target prediction of overexpressed microRNAs from LPS-challenged zebrafish (Danio rerio) treated with the novel anti-inflammatory peptide TnP. International Journal of Molecular Sciences, v. 22, p. 1-18 (2021).
  24. Disner GR, Falcão MAP, Lima C, Lopes-Ferreira M. Zebrafish Beyond the Bench: The -Plataforma Zebrafish Open Doors? Programme. Atla-Alternatives to Laboratory Animals, v. 49, p. 175-181 (2021).
  25. Disner GR, Lopes-Ferreira M, Lima C. Where the aryl hydrocarbon receptor meets the microRNAs’: literature review of the last 10 years. Frontiers in Molecular Biosciences, v. 8, p. 1-13 (2021).
  26. Do Nascimento SM, De Oliveira UC, Nishiyama-Jr MY, Tashima AK, Da Silva Junior PI. Presence of a neprilysin on Avicularia juruensis (Mygalomorphae: Theraphosidae) venom. Toxin Reviews, v. 1, p. 1-10 (2021).
  27. Dos Santos SR, Miranda A & da Silva Junior PI. Ovipin: a chicken eggs antibiotic agent. bioRxiv – Preprint (2021)
  28. Duzzi B, Silva CCF, Kodama RT, Cajado-Carvalho D, Squaiella-Baptistão CC, Portaro FCV. New Insights into the Hypotensins from Tityus serrulatus Venom: Pro-Inflammatory and Vasopeptidases Modulation Activities.Toxins (Basel). Nov 26;13(12):846 (2021).
  29. Eto SF, Fernandes DC, Baldassi AC, Balbuena TS, Da Costa Alecrim JV, Almeida de Carvalho FC, Lima C, Lopes-Ferreira M, Pizauro JM. Proteomic analysis capsule synthesis and redox mechanisms in the intracellular survival of group B Streptococcus in fish microglia. Fish & Shellfish Immunology, v. 118, p. 34-50 (2021).
  30. Falcão MAP, Banderó WCI, Disner GR, Batista-Feilho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M. Knockdown of miR-26a in zebrafish leads to impairment of the anti-inflammatory function of TnP in the control of neutrophilia. Fish & Shellfish Immunology, v. 114, p. 301-310 (2021).
  31. Fenero CM, Amaral MA, Xavier IK, Padovani BN, Paredes LC, Takiishi T, Lopes-Ferreira M, Lima C, Colombo A, Saraiva NO. Short chain fatty acids (SCFAs) improves TNBS-induced colitis in zebrafish. Current Research in Immunology, v. 2, p. 142-154 (2021).
  32. Figueiredo D, Santos WS, Montoni F, Iwai LK, Silva Junior PI. Toposome: Source of antimicrobial molecules in the gonads of the sea urchin Lytechinus variegatus (Lamarck, 1816). Fish Shellfish Immunol. Feb;109:51-61 (2021).
  33. Florentino PTV, Mendes D, Vitorino FNL, Martins DJ, Da Cunha JPC, Mortara RA, Menck CFM. DNA damage and oxidative stress in human cells infected by Trypanosoma cruzi. PLoS Pathog Apr;17(4):e1009502 (2021).
  34. Francisquini R, Berton R, Soares SG, Pessotti DS, Camacho MF, Andrade-Silva D, Barcick U, Serrano SMT, Chammas R, Nascimento MCV, Zelanis A. Community-based network analyses reveal emerging connectivity patterns of protein-protein interactions in murine melanoma secretome. J Proteomics. 232:104063 (2021).
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2020

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  31. Moreira RJ, Castro É, Oliveira TE, Belchior T, Peixoto AS, Chaves-Filho AB, Moreno MF, Lima JD, Yoshinaga M, Miyamoto S, Morais MRPT, Zorn TMT, Cogliati B, Iwai LK, Palmisano G, Cabral FJ, Festuccia W. Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis Are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. Mol Nutr Food Res, e1900833 Jan 24 (2020)
  32. Pessotti DS, Andrade-Silva D, Serrano SMT, Zelanis A. Heterotypic signaling between dermal fibroblasts and melanoma cells induces phenotypic plasticity and proteome rearrangement in malignant cells. Biochim Biophys Acta Proteins Proteom. 1868(12):140525 (2020).
  33. Sant’Anna MB, Giardini AC, Ribeiro MAC, Lopes FSR, Teixeira NB, Kimura LF, Bufalo MC, Ribeiro OG, Borrego A, Cabrera WHK, Ferreira JCB, Zambelli VO, Sant’Anna OA, Picolo G. The Crotoxin: SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions. Front Immunol. Oct 28; 11:591563 (2020).
  34. Schmidt MCB, Morais KLP, Almeida MES, Iqbal A, Goldfeder MB, Chudzinski-Tavassi. Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells. Cell Adhesion & Migration 14(1):129-138 (2020).
  35. Teixeira NB, Sant’Anna MB, Giardini AC, Araujo LP, Fonseca LA, Basso AS, Cury Y, Picolo G. Crotoxin down-modulates pro-inflammatory cells and alleviates pain on the MOG35-55-induced experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. Brain Behav Immun. Feb;84:253-268 Epub 2019 Dec 13 (2020)
  36. Teixeira NB, Picolo G, Giardini AC, Boumezbeur F, Pottier G, Kuhnast B, Servent D, Benoit E. Alterations of peripheral nerve excitability in an experimental autoimmune encephalomyelitis mouse model for multiple sclerosis. J Neuroinflammation. 2020 Sep 7;17(1):266 (2020).
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  38. Villas-Boas IM, Pidde G, Lichtenstein F, Ching ATC, Junqueira-de-Azevedo ILM, DeOcesano-Pereira C, Madureira Trufen CE, Chudzinski-Tavassi AM, Morais KLP, Tambourgi DV. Human Chondrocyte Activation by Toxins from Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature. Front Immunol. Sep;11:2191 (2020).
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2019

  1. Alvarez-Flores MP, Hébert A, Gouelle C, Geller S, Chudzinski-Tavassi AM, Pellerin L. Neuroprotective effect of rLosac on supplement-deprived mouse cultured cortical neurons involves maintenance of monocarboxylate transporter MCT2 protein levels. J Neurochem. Jan;148(1):80-96 (2019)

 

  1. Barreto Dos Santos N, Bonfanti AP, Rocha-E-Silva TAAD, da Silva PI Jr, da Cruz-Höfling MA, Verinaud L, Rapôso C. Venom of the Phoneutria nigriventer spider alters the cell cycle, viability, and migration of cancer cells. J Cell Physiol, v. 234, p. 1398-1415 (2019)

 

  1. Boufleur P, Sciani JM, Goldfeder M, Faria F, Branco V, Chudzinski-Tavassi AM. Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. Eur J Drug Metab Pharmacokinet. Feb;44(1):111-120 (2019)

 

  1. Boufleur P, Sciani JM, Goldfeder M, Faria F, Branco V, Chudzinski-Tavassi AM. Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. Eur J Drug Metab Pharmacokinet. Aug 21. Feb;44(1):111-120 (2019)

 

  1. Cajado-Carvalho D, da Silva CCF, Kodama RT, Mariano DOC, Pimenta DC, Duzzi B, Kuniyoshi AK, Portaro FV. Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom. Toxins (Basel). Mar 31;11(4). pii: E194 (2019)

 

  1. Charlie-Silva I, Klein A, Gomes JMM, Prado EJR, Moraes AC, Eto SF, Fernandes DC, Fagliari JJ, Junior JDC, Lima C, Lopes-Ferreira M, Conceição K, Manrique WG, Belo MAA. Acute-phase proteins during inflammatory reaction by bacterial infection: Fish-model. Sci Rep. Mar 18;9(1):4776 (2019)

 

  1. Dal Mas C, Rossato L, Shimizu T, Oliveira EB, da Silva Junior PI, Meis JF, Colombo AL, Hayashi MAF. Effects of the Natural Peptide Crotamine from a South American Rattlesnake on Candida auris, an Emergent Multidrug Antifungal Resistant Human Pathogen. Biomolecules. May 28;9(6). pii: E205 (2019)

 

  1. de Araujo CB, Calderano SG, Elias MC. The Dynamics of Replication in Trypanosoma cruzi Parasites by Single-Molecule Analysis. J Eukaryot Microbiol. May;66(3):514-518 (2019)

 

  1. de Araujo CB, de Lima LP, Calderano SG, Silva Damasceno F, Silber AM, Elias MC. Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the Trypanosoma cruzi Life Cycle and Blocks Parasite Infectivity. Antimicrob Agents Chemother. Apr 25;63(5). pii: e01806-18 (2019)

 

  1. de Lima LP, Calderano SG, da Silva MS, de Araujo CB, Vasconcelos EJR, Iwai LK, Pereira CA, Fragoso SP, Elias MC. Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi. Sci Rep. Feb 27;9(1):2888 (2019)

 

  1. Díaz-Roa A, Espinoza-Culupú A, Torres-García O, Borges MM, Avino IN, Alves FL, Miranda A, Patarroyo MA, da Silva PI Jr, Bello FJ. Sarconesin II, a New Antimicrobial Peptide Isolated from Sarconesiopsis magellanica Excretions and Secretions. Molecules. May 31;24(11). pii: E2077 (2019)

 

  1. Dos Santos TB, Soares JDM, Lima JE, Silva JC, Ivamoto ST, Baba VY, Souza SGH, Lorenzetti APR, Paschoal AR, Meda AR, Nishiyama Júnior MY, de Oliveira ÚC, Mokochinski JB, Guyot R, Junqueira-de-Azevedo ILM, Figueira AVO, Mazzafera P, Júnior OR, Vieira LGE, Pereira LFP, Domingues DS. An integrated analysis of mRNA and sRNA transcriptional profiles in Coffea arabica L. roots: insights on nitrogen starvation responses. Funct Integr Genomics. Jan;19(1):151-169 (2019)

 

  1. Esteves E, Bizzarro B, Costa FB, Ramírez-Hernández A, Peti APF, Cataneo AHD, Wowk PF, Timóteo RP, Labruna MB, Silva Junior PI, Silva CL, Faccioli LH, Fogaça AC, Sorgi CA, Sá-Nunes A. Amblyomma sculptum Salivary PGE2 Modulates the Dendritic Cell-Rickettsia rickettsii Interactions in vitro and in vivo. Frontiers in Immunology, v. 10, p. 118 (2019)

 

  1. Gren ECK, Kitano ES, Andrade-Silva D, Iwai LK, Reis MS, Menezes MC, Serrano SMT. Comparative analysis of the high molecular mass subproteomes of eight Bothrops snake venoms. Comp Biochem Physiol Part D Genomics Proteomics.Jan 30; 30:113-121 (2019)

 

  1. Kimura LF, Mattaraia VGM, Picolo G. Distinct environmental enrichment protocols reduce anxiety but differentially modulate pain sensitivity in rats. Behav Brain Res. May 17; 364:442-446 (2019)

 

  1. Liberato T, Fukushima I, Kitano ES, Serrano SMT, Chammas R, Zelanis A. Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using Terminal Amine Isotopic Labeling of Substrates. J Proteomics. 2019 Feb 10; 192:291-298 (2019)

 

  1. Lopes PH, Murakami MT, Portaro FCV, Mesquita Pasqualoto KF, van den Berg C, Tambourgi DV.Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. J Enzyme Inhib Med Chem. Dec;34(1):310-321 (2019)

 

  1. Luchini LSG, Pidde G, Squaiella Baptistao CC, Tambourgi DV. Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake. Front. Immunol. 10: 1137- 1148 (2019)

 

  1. Meneguello L, Barbosa NM, Pereira KD, Proença ARG, Tamborlin L, Simabuco FM, Iwai LK, Zanelli CF, Valentini SR, Luchessi AD. The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions. J Cell Biochem. Apr;120(4):6015-6025 (2019)

 

  1. Menezes MC, Kitano ES, Bauer VC, Oliveira AK, Cararo-Lopes E, Nishiyama MY Jr, Zelanis A, Serrano SMT. Early response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom. J Proteomics. Apr 30; 198:163-176 (2019)

 

  1. Monteiro Dos Santos J, Cardoso Dos Santos J, Marques EE, Araújo GC, Seibert CS, Lopes-Ferreira M, Lima C. Stingray (Potamotrygon rex) maturity is associated with inflammatory capacity of the venom. Toxicon. May; 163:74-83 (2019)

 

  1. Oliveira EB, Farias KJS, Gomes DL, Araújo JG, Dias da Silva W, Oliveira Rocha HA, Donadi EA, Pedrosa, MFF, Crispim JCO. Tityus serrulatus scorpion venom induces apoptosis in cervical cancer cell lines. Evidence-Based Complementary and Alternative Medicine. June 2019. (In press)

 

  1. Pereira GJV, Tavares MT, Azevedo RA, Martins BB, Cunha MR, Bhardwaj R, Cury Y, Zambelli VO, Barbosa EG, Hediger MA, Parise-Filho R. Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling. Bioorg Med Chem. 2019 May 14. pii: S0968-0896(19)30087-2 (2019)

 

  1. Reis MS, Estrela G, Ferreira CE, Barrera J. Optimal Boolean lattice-based algorithms for the U-curve optimization problem. Information Sciences 471, 97–114 (2019)

 

  1. Sidoli s, Kori y, Lopes M, Yuan ZY, Kim HJ, Kulej K, Janssen K, Agosto L, da Cunha JPC and Garcia BA. One minute analysis of histone post-translational modifications by direct infusion mass spectrometry. Genome Research, in press.

 

  1. Silva-de-França F, Villas-Boas IM, Serrano SMT, Cogliati B, Chudzinski SAA, Lopes PH, Kitano ES, Okamoto CK, Tambourgi DV. Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation. PLoS Negl Trop Dis.Jan 18;13(1):e0007017 (2019)

 

  1. Tavernelli LE, Motta MCM, Gonçalves CS, da Silva MS, Elias MC, Alonso VL, Serra E, Cribb P. Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity. Sci Rep. Jan 17;9(1):192 (2019)

 

  1. Teixeira CMM, Correa CN, Iwai LK, Ferro ES, Castro LM. Characterization of Intracellular Peptides from Zebrafish (Danio rerio) Brain. Zebrafish. Jun;16(3):240-251 (2019)

 

  1. Teixeira SC, Lopes DS, da Silva MS, da Luz FAC, Gimenes SNC, Borges BC, da Silva AA, Martins FA, Dos Santos MA, Teixeira TL, Oliveira RAO, Ávila VMR, Silva MJB, Elias MC, Martin R, da Silva CV, Knölker HJ. Pentachloropseudilin Impairs Angiogenesis by Disrupting Actin Cytoskeleton, Integrin Trafficking and Cell Cycle. Chembiochem. 2019 Apr 26 (2019)

 

  1. Vieira ML, Persson S, Lopes-Ferreira M, Romero EC, Kirchgatter K, Nascimento ALTO, Herwald H. Heparin-Binding Protein Release Is Strongly Induced by Leptospira Species and Is a Candidate for an Early Diagnostic Marker of Human Leptospirosis. J Infect Dis. Feb 23;219(6):996-1006 (2019)

 

  1. Zelanis A, Andrade-Silva D, Kitano ES, Liberato T, Fukushima I, Serrano SMT, Tashima AK. A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics. May 2019 (in press)

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2018

  1. Alencar-Couto MN, Amadeu- Megale, AA, Magnoli, FC, Magalhães-Junior, MJ, da Silva, SG, Kanashiro, MM, Dias da Silva, W. Development of monoclonal antobody anti-Africam Bitis arietans snake toxin phospholipase A2. J. Toxins, 4:Issue 1, ISSN 2328-1723 (2018)

 

  1. Alves CL, Repolês BM, da Silva MS, Mendes IC, Marin PA, Aguiar PHN, Santos SDS, Franco GR, Macedo AM, Pena SDJ, Andrade LO, Guarneri AA, Tahara EB, Elias MC, Machado CR. The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi.Sci Rep. Sep 6;8(1):13335. (2018)

 

  1. Alves CRR, Faria DP, Carneiro CG, Garcez AT, Gutierrez VP, das Neves W, de Almeida NR, Cury Y, Chammas R, Brum PC. 18F-Fluoride PET/CT and 99mTc-MDP SPECT/CT can detect bone cancer at early stage in rodents. Life Sci. May 171;206:29-34 (2018)

 

  1. Amazonas DR, Portes-Junior JA, Nishiyama-Jr MY, Nicolau CA, Chalkidis HM, Mourão RHV, Grazziotin FG, Rokyta DR, Gibbs HL, Valente RH, ILM, Moura-da-Silva AM. Molecular mechanisms underlying intraspecific variation in snake venom. J Proteomics. Jun 15;181:60-72 (2018)

 

  1. Andrade-Silva D, Ashline D, Tran T, Lopes AS, Cardoso SRT, Reis MS, Zelanis A, Serrano SMT, Reinhold VN. Structures of N-Glycans of Bothrops venoms revealed as molecular signatures that contribute to venom phenotype in viperid snakes. Mol Cell Proteomics. 2018 Jul;17(7):1261-1284 (2018)

 

  1. Araldi RP, Maristela Oliveira dos Santos, Fabiane FariaBarbon, Bruna Aparecida Manjerona, Bruno Rosa Meirelles, Pedro de Oliva Neto, Pedro Ismael da Silva Júnior, Lucinéia dos Santos, Isabel Cristina Cherici Camargo, Edislane Barreiros de Souza., Analysis of antioxidant, cytotoxic and mutagenic potential of Agave sisalana Perrine extracts using Vero cells, human lymphocytes and mice polychromatic erytrocytes.  Biomedicine & Pharmacotherapy – Vol 98, Pg. 873-885 Fev  (2018)

 

  1. Atashpaz-Gargari, E.; Reis, M.S.; Barrera, J.; Braga-Neto, U.M.; Dougherty, E.R. A fast algorithm for U-curve branch-and-bound feature selection. Pattern Recognition, v. 73, p. 172–188 (2018)

 

  1. Benatti FB, Miyake CNH, Dantas WS, Zambelli VO, Shinjo SK, Pereira RMR, Silva MER, Sá-Pinto AL, Borba E, Bonfá E, Gualano B. Exercise Increases Insulin Sensitivity and Skeletal Muscle AMPK Expression in Systemic Lupus Erythematosus: A Randomized Controlled Trial. Front Immunol. Apr 27;9:906 eCollection (2018)

 

  1. Bensaoud C, Nishiyama MY Jr, Ben Hamda C, Lichtenstein F, Castro de Oliveira U, Faria F, Loiola Meirelles Junqueira-de-Azevedo I, Ghedira K, Bouattour A, M’Ghirbi Y, Chudzinski-Tavassi AM. De novo assembly and annotation of Hyalomma dromedarii tick (Acari: Ixodidae) sialotranscriptome with regard to gender differences in gene expression. Parasit Vectors.  May 24;11(1):314 (2018)

 

  1. Beraldo Neto E, Mariano DOC, Freitas LA, Dorce ALC, Martins AN, Pimenta DC, Portaro FV, Cajado-Carvalho D, Dorce VAC, Nencioni ALA. a Fraction Isolated from Tityus bahiensis Scorpion Venom, Alters Cytokines Level and Induces Seizures When Intrahippocampally Injected in Rats. Toxins (Basel). Jun 19;10(6) (2018)

 

  1. Borges AR, Toledo DA, Fermino BR, de Oliveira JC, Silber AM, Elias MC, D’Avila H, Scopel KKG. In Vitro Cellular Division of Trypanosoma abeli Reveals Two Pathways for Organelle Replication. J Eukaryot Microbiol. 2019 May;66(3):385-392 (2018)

 

  1. Cia MC, de Carvalho G, Azevedo RA, Monteiro-Vitorello CB, Souza GM, Nishiyama-Junior MY, Lembke CG, Antunes de Faria RSDC, Marques JPR1, Melotto M, Camargo LEA. Novel Insights Into The Early Stages Of Ratoon Stunting Disease Of Sugarcane Inferred From Transcript And Protein Analysis. Phytopathology V. 108, P. 8 (2018)

 

  1. Crispim M, Damasceno FS, Hernández A, Barisón MJ, Pretto Sauter I, Souza Pavani R, Santos Moura A, Pral EMF, Cortez M, Elias MC, Silber AM. The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection. PLoS Negl Trop Dis. Jan 10;12(1):e0006170 (2018)

 

  1. da Silva LB, Menezes MC, Kitano ES, Oliveira AK, Abreu AG, Souza GO, Heinemann MB, Isaac L, Fraga TR, Serrano SMT, Barbosa AS. Leptospira interrogans secreted proteases degrade extracellular Matrix and plasma proteins from the host. Front Cell Infect Microbiol. Mar 27;8:92 (2018)

 

  1. da Silva MS, Hovel-Miner GA, Briggs EM, Elias MC, McCulloch R. Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes.PLoS Pathog. Nov 15;14(11):e1007321. eCollection. Review. (2018)

 

  1. Damasceno KC, Cavalcante AK, Maziero JS, Martini GA, Ormênio MB, Mamede FC, Miranda CS, Campello FA, Izidoro JC, Rogero SO, Fungaro DA, Lopes-Ferreira M, Rogero JR. In vitro and in vivo toxicity of coal fly Ash Lechatee. Ecotoxicol. Environ. Contam. v. 13, n. 1, 2018, 73-78 (2018)

 

  1. de Luna Vitorino FN, Montoni, F, Moreno, JN, et al. FGF2 Antiproliferative Stimulation Induces Proteomic Dynamic Changes and High Expression of FOSB and JUNB in K-Ras-Driven Mouse Tumor Cells. Proteomics   Sep;18(17):e1800203. Epub 2018 Aug 14. (2018)

 

  1. De Oliveira Santos J, Zuma AA, de Luna Vitorino FN, da Cunha, JPC, de Souza, W, Motta, MCM. Trichostatin A induces Trypanosoma cruzi histone and tubulin acetylation: effects on cell division and microtubule cytoskeleton remodelling. Parasitology, v. 13, p. 1-10. (2018)

 

  1. de Oliveira UC, Nishiyama MY Jr, Dos Santos MBV, Santos-da-Silva AP, Chalkidis HM, Souza-Imberg A, Candido DM, Yamanouye N, Dorce VAC, Junqueira-de-Azevedo ILM. Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. PLoS One. Mar 21;13(3):e0193739 (2018)

 

  1. de Souza GS, Rodriguez ABF, Romano MI, Ribeiro ES, Oelemann WMR, Rocha DG, Dias da Silva W, Lassunskaia EB. Identification of the Apa protein secreted by Mycobacterium avium subsp. Paratuberculosis as a novel fecal biomarker for Johne´s disase in cattle. Pathogen and Disease, Aug 1;76(6) (2018)

 

  1. Delafontaine M, Panfil C, Spöler F, Kray S, Burgher F, Mathieu L, Blomet J, Schrage NF, Tambourgi DV. The Ex vivo Eye Irritation Test (EVEIT) model as a mean of improving venom ophthalmia understanding. Toxicon. Jun 8;150:253-260 (2018)

 

  1. Dias MH, Fonseca CS, Zeidler JD, Albuquerque LL, da Silva MS, Cararo-Lopes E, Reis MS, Noël V, Dos Santos EO, Prior IA, Armelin HA. Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. Mol Oncol. 2019 Feb;13(2):290-306 (2018)

 

  1. Díaz-Roa A, Patarroyo MA, Bello FJ, Da Silva PI Jr. Sarconesin: Sarconesiopsis magellanicaBlowfly Larval Excretions and Secretions With Antibacterial Properties. Front Microbiol. Sep 28;9:2249. eCollection (2018)

 

  1. Diniz LCLMiranda Ada Silva PI Jr. Human Antimicrobial Peptide Isolated From Triatoma infestansHaemolymph, Trypanosoma cruzi-Transmitting Vector. Front Cell Infect Microbiol.  Oct 30;8:354. eCollection (2018)

 

  1. Diniz MRV, Paiva ALB , Guerra-Duarte C, Nishiyama Junior MY, Mudadu MA, Oliveira UC , Borges MH, Yates JR, Junqueira-de-Azevedo, ILM. An overview of Phoneutria nigriventer spider venom using combined transcriptomic and proteomic approaches. PLoS One Aug;13(8):e0200628 (2018)

 

  1. Farias IB, Morais-Zani K, Serino-Silva C, Sant’Anna SS, Rocha MMTD, Grego KF, Andrade-Silva D, Serrano SMT, Tanaka-Azevedo AM. Functional and proteomic comparison of Bothrops jararaca venom from captive specimens and the Brazilian Bothropic Reference Venom. J Proteomics. Mar 1;174:36-46 (2018)

 

  1. Ferreira Junior WA, Zaharenko AJ, Kazuma K, Picolo G, Gutierrez VP, de Freitas JC, Konno K, Cury Y. Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391. Toxins 10(1), 12. (2018)

 

  1. Florentino PTV, Real F, Orikaza CM, da Cunha JPC, Vitorino FNL, Cordero EM, Sobreira TJP, Mortara RA. A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes. Front Microbiol. Apr 10;9:693 (2018)

 

  1. Galvão da Silva BAV, Chudzinski-Tavassi AM, Pasqualoto KFM. A Combined Computer-Aided Approach to Drive the Identification of Potential Epitopes in Protein Therapeutics. J Pharm Pharm Sci. 21(1):268-285 (2018)

 

  1. Gatti da Silva GH, Jurica M, Chagas da Cunha JP, Oliveira CC, Coltri PP. Human RNF113A participates of pre-mRNA splicing in vitro. Journal of Cellular Biochemestry. v. 1, p. 1-11 (2018)

 

  1. Ikeda MAK, de Almeida JPF, Jannuzzi GP, Cronemberg-Andrade A, Torrecilhas ACT, Moretti NS, da Cunha JPC, de Almeida SR, Ferreira KS. Extracellular Vesicles From Sporothrix brasiliensis Are an Important Virulence Factor That Induce an Increase in Fungal Burden in Experimental Sporotrichosis. Frontiers in Microbiology, v. 9, p. 2286-2289 (2018)

 

  1. Ikegami A, Teixeira LFS, Braga SM, et al. Knockdown of NF-kappa B1 by shRNA Inhibits the Growth of Renal Cell Carcinoma In Vitro and In Vivo. Oncology Research. 26(5) 743-751 (2018)

 

  1. Kimura LF, Santos-Neto M, Barbaro KC, Picolo G. Potamotrygon motoro stingray venom induces both neurogenic and inflammatory pain behavior in rodents. Toxicon. Aug;150:168-174 (2018)

 

  1. Leda AR, Hunter J, Oliveira UC, Junqueira-de-Azevedo ILM, Araripe Sucupira MC, Diaz R. Sobhie Insights about minority HIV-1 strains in transmitted drug resistance mutation dynamics and disease progression Journal of Antimicrobial Chemotherapy. Jul;73(7):1930-4 (2018)

 

  1. Liberato T, Pessotti DS, Fukushima I, Kitano ES, Serrano SMT, Zelanis A. Signatures of protein expression revealed by secretome analyses of cancer associated fibroblasts and melanoma cell lines. J Proteomics. Mar 1;174:1-8 (2018)

 

  1. Lima SC, Porta LC, Lima ÁDC, Campeiro JD, Meurer Y, Teixeira NB, Duarte T, Oliveira EB, Picolo G, Godinho RO, Silva RH, Hayashi MAF.Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles. PLoS Negl Trop Dis. Aug 6;12(8):e0006700 (2018)

 

  1. Lomazi RL, ES Nishiduka, PI Silva, AK Tashima. Identification of Peptides in Spider Venom Using Mass Spectrometry (Chapter – Feb 2018 – Methods in molecular biology (Clifton, N.J.) Peptidomics, 359-367 (2018)

 

  1. Mancuso RI, Miyaji EN, Silva CCF, Portaro FV, Soares-Schanoski A, Ribeiro OG, Oliveira MLS. Impaired expression of CXCL5 and matrix metalloproteinases in the lungs of mice with high susceptibility to Streptococcus pneumoniae infection. Immun Inflamm Dis. Mar;6(1):128-142 (2018)

 

  1. Manzoni-de-Almeida D, Squaiella-Baptistão CC, Lopes PH, van den Berg CW, Tambourgi DV. Loxosceles venom Sphingomyelinase D activates human blood leukocytes: Role of the complement system. Mol Immunol. Feb;94:45-53 (2018)

 

  1. Maria DA, Will SEAL, Bosch RV, Souza JG, Sciani JM, Goldfeder MB, Rondon GG, Chudzinski-Tavassi AM. Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity. Toxicol Rep. Dec 1;6:51-63. eCollection (2018)

 

  1. Marin PA, da Silva MS, Pavani RS, Machado CR, Elias MC. Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment. Sci Rep. Mar 29;8(1):5405 (2018)

 

  1. Megale AAA, Magnoli FC, Kuniyoshi AK, Iwai LK, Tambourgi DV, Portaro FCV, da Silva WD. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities. J Venom Anim Toxins Incl Trop Dis. Dec 13; 24:38 (2018)

 

  1. Miyake CNH, Gualano B, Dantas WS, Pereira RT, Neves W, Zambelli VO, Shinjo SK, Pereira RM, Silva ER, Sá-Pinto AL, Borba E, Roschel H, Bonfá E, Benatti FB. Increased Insulin Resistance and Glucagon Levels in Mild/Inactive Systemic Lupus Erythematosus Patients Despite Normal Glucose Tolerance.  Arthritis Care Res (Hoboken). Jan;70(1):114-124 (2018)

 

  1. Oliveira DBL, Durigon GS, Mendes ÉA, Ladner JT, Andreata-Santos R, Araujo DB, Botosso VF, Paola ND, Neto DFL, Cunha MP, Braconi CT, Alves RPS, Jesus MR,Pereira LR, Melo SR, Mesquita FS, Silveira VB, Thomazelli LM, Favoretto SR, Almonfrey FB, Abdulkader RCRM, Gabrili JM, Tambourgi DV, Oliveira SF, Prieto K, Wiley MR, Ferreira LCS, Silva MV, Palacios GF, Zanotto PMA, Durigon EL. Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System. Viruses. Nov 7;10(11) (2018)

 

  1. Oliveira PRS, França FS, Villas Boas IM, Rocha MMTD, Sant’Anna SS, Bastos ML, Tambourgi DV. Snake venoms from Angola: Intra-specific variations and immunogenicity. Toxicon. 148: 85-94 (2018)

 

  1. Passaia, B.D.S., Dias, M.H., Kremer, J.L., Antonini, S.R.R., Almeida, M.Q.D., Fragoso, M.C.B.V. and Lotfi, C.F.P. TcF21/POD-1, a Transcritional regulator of sF-1/nr5a1, as a Potential Prognosis Marker in adult and Pediatric adrenocortical Tumors. Frontiers in Endocrinology, 9, p.38 (2018)

 

  1. Pavani RS, Vitarelli MO, Fernandes CAH, Mattioli FF, Morone M, Menezes MC, Fontes MRM, Cano MIN, Elias MC. Replication Protein A-1 Has a Preference for the Telomeric G-rich Sequence in Trypanosoma cruzi. J Eukaryot Microbiol. May;65(3):345-356 (2018)

 

  1. Pavon LF, Sibov TT, Caminada de Toledo SR, Mara de Oliveira D, Cabral FR, Gabriel de Souza J, Boufleur P, Marti LC, Malheiros JM, Ferreira da Cruz E, Paiva FF, Malheiros SMF, de Paiva Neto MA, Tannús A, Mascarenhas de Oliveira S, Silva NS, Cappellano AM, Petrilli AS, Chudzinski-Tavassi AM, Cavalheiro S. Establishment of primary cell culture and an intracranial xenograft model of pediatric ependymoma: a prospect for therapy development and understanding of tumor biology. Oncotarget. Apr 24;9(31):21731-21743 (2018)

 

  1. Pavon LF, Sibov TT, de Souza AV, da Cruz EF, Malheiros SMF, Cabral FR, de Souza JG, Boufleur P, de Oliveira DM, de Toledo SRC, Marti LC, Malheiros JM, Paiva FF, Tannús A, de Oliveira SM, Chudzinski-Tavassi AM, de Paiva Neto MA, Cavalheiro S. Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo. Stem Cell Res Ther. Nov 9;9(1):310 (2018)

 

  1. Pilar TV, Florentino, FR, Orikaza CM, da Cunha JPC, Vitorino FNL, Cordero EM, Sobreira TJP, Mortara RA. A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes.Frontiers in Microbiology , v. 9, p. 1-7 (2018)

 

  1. Ribeiro KS, Vasconcellos CI, Soares RP, Mendes MT, Ellis CC, Aguilera-Flores M, de Almeida IC, Schenkman S, Iwai LK, Torrecilhas AC. Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells. J Extracell Vesicles. Apr 17;7(1):1463779 (2018)

 

  1. Rostelato-Ferreira SR, Chariston A Dal Belo, Pedro I Silva Jr, Stephen Hyslop, Lea Rodrigues-Simioni, Thomaz AA Rocha-e-Silva. Presynaptic Activity of an Isolated Fraction from Rhinella Schneideri Presynaptic Activity of an Isolated Fraction from Rhinella schneideri Poison. Adv Pharm Bull. Aug; 8(3): 517–522 (2018)

 

  1. Schmidt MCB, Morais KLP, Almeida MES, Iqbal A, Goldfeder MB, Chudzinski-Tavassi AM. Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells. Cell Adh Migr. Sep 25:1-10 (2018)

 

  1. Segura-Ramírez PJ, and Silva Júnior PI. Loxosceles gaucho Spider Venom: An Untapped Source of Antimicrobial Agents Toxins 10(12), 522 (2018)

 

  1. Serrano SMT, Zelanis A, Kitano ES, Tashima AK. Analysis of the snake venom peptidome. Methods Mol Biol.1719:349-358 (2018)

 

  1. Silva MA, Lopes DS, Teixeira SC, Gimenes SNC, Azevedo FVPV, Polloni L, Borges BC, da Silva MS, Barbosa MJ, Oliveira Júnior RJ, Elias MC, da Silva CV, Yoneyama KAG, Rodrigues VM, Rodrigues RS. Genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells.Int J Biol Macromol. Oct 15;118(Pt A):311-319 (2018)

 

  1. Souza GS, Rodriguez ABF, Romário NI, Ribeiro S, Oelemann WMR, Rocha DG, Dias da Silva, W. Lassunskaia EB. Identification of the Apa protein secreted by Mycobacterium avium subsp. Paratuberculosis as a novel fecal biomarker for Johne´s disase in cattle. Pathogen and Disease, Volume 76, Issue 6, August fty063. (2018)

 

  1. Squaiella-Baptistão CC, Magnoli FC, Marcelino JR, Sant’Anna OA, Tambourgi DV. Quality of horse F(ab’)2 antitoxins and anti-rabies immunoglobulins: protein content and anticomplementary activity. J Venom Anim Toxins Incl Trop Dis, vol.24, 16 (2018)

 

  1. Squaiella-Baptistão CC, Sant’Anna OA, Marcelino JR, Tambourgi DV. The history of antivenoms development: Beyond Calmette and Vital Brazil. Toxicon 150: 86-95 (2018)

 

  1. Torres MDT, Pedron CN, Higashikuni Y, Kramer RMCardoso MHOshiro KGNFranco OLSilva Junior PISilva FDOliveira Junior VXLu TKde la Fuente-Nunez C. Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. CommunDec 7;1:221. eCollection (2018)

 

  1. Torres-Bonilla KA, Andrade-Silva D, Serrano SM, Hyslop S. Comp. Biochemical characterization of venom from Pseudoboa neuwiedii (Neuwied􏰀s false boa; Xenodontinae; Pseudoboini). Biochem. Physiol. C. Toxicol. Pharmacol. Jun 30;213:27-38 (2018)

 

  1. Valente RH, Luna MS, Oliveira UC, Nishiyama Junior MY, Junqueira-de-Azevedo ILM, Portes Júnior JÁ, Clissa PB, Viana LG, Sanches L, Moura-da-Silva AM, Perales JEA, Yamanouye N. Bothrops jararaca accessory venom gland is an ancillary source of toxins to the snakeJournal of Proteomics. Apr;177:137-47 (2018)

 

  1. Vitorino; F.N.L.; Montoni, F.; Moreno, J.N.; Souza, B.F.; Lopes, M.C.; Cordeiro, B.; Fonseca, C.S.; Gilmore, J.M.; Sardiu, M.I.; Reis, M.S.; Florens, L.A.; Washburn, M.P.; Armelin, H.A.; da Cunha, J.P.C. FGF-2 antiproliferative stimulus induces proteomics dynamics changes and high expression of fosB and junB in K-Ras-driven mouse tumor cells. Proteomics. 2018 Jul 23 v. 23, p. 1800203. (2018)

 

  1. Walter, J.M.; Lopes, F.A.C.; Lopes-Ferreira, M.; Vidal, L.M.; Leomil, L.; Melo, F.; De Azevedo, Girlene S.; Oliveira, R.M.S.; Medeirtos, A.J.; Melo, A.S.O.; De Rezende, C.E.; Tanuri, A.; Thompson, F.L. Occurrence of Harmful Cyanobacteria in Drinking Water from a Severely Drought-Impacted Semi-arid Region. Frontiers in Microbiology, v. 9, p. 176-185 (2018)

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2017

  1. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press (2016).
  2. Abreu TF, Sumitomo BN, Nishiyama MY Jr, Oliveira UC, Souza GH, Kitano ES, Zelanis A, Serrano SM, Junqueira-de-Azevedo I, Silva PI Jr, Tashima AK. Peptidomics of Acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity. J Proteomics 151:232-242 (2017).
  3. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press.
  4. Araujo TL, Zeidler JD, Oliveira PV, Dias MH, Armelin HA, Laurindo FR. Protein disulfide isomerase externalization in endothelial cells follows classical and unconventional routes. Free Radic Biol Med.103:199-208 (2017).
  5. Campos JC, Queliconi BB, Bozi LH; Bechara LR, Dourado PM, Andres A M, Jannig PR, Gomes KM, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB. Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy (Georgetown, TX), in press.
  6. Candido-Ferreira IL, Kronenberger T, Sayegh RS, Batista IF, da Silva Junior PI. Evidence of an antimicrobial peptide signature encrypted in HECT E3 ubiquitin ligases Frontiers Immunology 9; 7:664 (2017).
  7. Chaves AF, Castilho DG, Navarro MV, Oliveira AK, Serrano SM, Tashima AK, Batista WL. Phosphosite-specific regulation of the oxidative-stress response of Paracoccidioides brasiliensis: a shotgun phosphoproteomic analysis. Microbes Infect. 19(1):34-46 (2017).
  8. da Silva MS, Munoz, PA, Armelin HA, Elias MC. Differences in the detection of BrdU/Edu incorporation assays alter the calculation for G1, S, and G2 phases of the cell cycle in Trypanosomatids. J Eukaryot Micorbiol 4: 1-14 (2017).
  9. da Silva MS, Segatto M, Pavani RS, Guitierrez-Rodrigues F, Bispo VD, de Medeiros MH, Calado RT, Elias MC, Cano MI. Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites. Biochim Biophys Acta 1864 (1): 138-150 (2017).
  10. Di Genova BM, da Silva RC, da Cunha JP, Gargantini PR, Mortara RA, Tonelli RR. Protein SUMOylation is Involved in Cell-cycle Progression and Cell Morphology in Giardia lamblia. J Eukaryot Microbiol. Nov 19 in press.
  11. Dias RG, Sampaio SC, Sant’Anna MB, Cunha FQ, Gutiérrez JM, Lomonte B, Cury Y, Picolo G. Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect. J. Venom Anim Toxins Incl Trop Dis. 23;23:18 (2017).
  12. Félix-Silva J, Gomes JA, Xavier-Santos JB, Passos JG, Silva-Junior AA, Tambourgi DV, Fernandes-Pedrosa M. Inhibition of local effects induced by Bothrops erythromelas snake venom: Assessment of the effectiveness of Brazilian polyvalent bothropic antivenom and aqueous leaf extract of Jatropha gossypiifolia. Toxicon, 125:74-83 (2017).
  13. Folle AM, Kitano ES, Lima A, Gil M, Cucher M, Mourglia-Ettlin G, Iwai LK, Rosenzvit M, Batthyány C, Ferreira AM. Characterisation of Antigen B Protein Species Present in the Hydatid Cyst Fluid of Echinococcus canadensis G7 Genotype. PLoS Negl Trop Dis. 3;11(1):e0005250 (2017).
  14. Gonzales-Zubiate FA, Okuda EK, Da Cunha JP, Oliveira CC. Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. J Biol Chem. jbc.M116.772376. in press
  15. Grund LZ, Novaski I, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R. Autoimmunity. 50(2):86-101 (2017).
  16. Iqbal A, Goldfeder MB, Marques-Porto R, Asif H, Souza JG, Faria F, Chudzinski-Tavassi AM. Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. Sci Rep. 3;7(1):1431 (2017).
  17. Katz ISS, Dias MH, Lima IF, Chaves LB, Ribeiro OG, Scheffer KC, Iwai LK. Large protein as a potential target for use in rabies diagnostic, Acta Virologica in press.
  18. Komegae EN, Souza TA, Grund LZ, Lima C, Lopes-Ferreira M. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis. PLoS One. 24;12(2):e0171796 (2017).
  19. Lopes PH, Rocha MT, Kuniyoshi AK, Portaro FV, Gonçalves LRC. Edema and Nociception Induced by Philodryas patagoniensis Venom in Mice: A Pharmacological Evaluation with Implications for the Accident Treatment. J. Pharmacol. Exp. Ther. 361(3): 349-354 (2017)
  20. Miyake CN, Gualano B, Dantas WS, Pereira RT, Neves W, Zambelli VO, Shinjo SK, Pereira RM, Silva ER, Sá-Pinto AL, Borba E, Roschel H, Bonfá E, Benatti FB. Increased insulin resistance and glucagon levels in mild/inactive systemic lupus patients despite normal glucose tolerance. Arthritis Care Res (Hoboken). 20 (2017).
  21. Monte ER, Rossato C, Llanos RP, Russo LC, de Castro LM, Gozzo FC, de Araujo CB, Peron JP, Sant’Anna OA, Ferro ES, Rioli V. Interferon-gamma activity is potentiated by an intracellular peptide derived from the human 19S ATPase regulatory subunit 4 of the proteasome. J Proteomics 16; 151:74-82 (2017).
  22. Nicolau CA, Carvalho PC, Junqueira-de-Azevedo IL, Teixeira-Ferreira A, Junqueira M, Perales J, Neves-Ferreira AG, Valente RH. An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca. J Proteomics. 16;151:214-231 (2017).
  23. Okamoto CK, van den Berg CW, Masashi M, Gonçalves-de-Andrade RM, Tambourgi DV. Tetracycline Reduces Kidney Damage Induced by Loxosceles Spider Venom. Toxins (Basel). 2;9(3) (2017).
  24. Pedron CN, Torres MDT, da Silva Lima JA, Silva PI, Silva FD, Oliveira VX. Novel designed VmCT1 analogs with increased antimicrobial activity. European Journal of Medicinal Chemistry 126, 456-463 (2017).
  25. Perazzo J, Lima C, Heras M, Bardají E, Lopes-Ferreira M, Castanho M. Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action. ACS Chem Neurosci in press.
  26. Russo LC, Araujo CB, Iwai LK, Ferro ES, Forti FL. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells. J Proteomics. 16;151:24-32 (2017).
  27. Sousa LF, Portes-Junior JA, Nicolau CA, Bernardoni JL, Nishiyama-Jr MY, Amazonas DR, Freitas-de-Sousa LA, Mourão RH, Chalkidis HM, Valente RH, Moura-da-Silva AM. Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon. Journal of Proteomics (Print), v. 1, p. 1, 2017. J Proteomics. 21;159:32-46 (2017).
  28. Teixiera SC, Lopes DS, Gimenes SN, Teixiera TL, da Silva MS, Brígido RT, da Luz FA, da Silva AA, Silva MA, Florentino PV, Tavares PC, dos Santos MA, Ávila VM, Silva MJ, Elias MC, Mortara RA, da Silva CV. Mechanistic Insights into the Anti-angiogenic Activity of Trypanosoma cruzi Protein 21 and its Potential Impact on the Onset of Chagasic Cardiomyopathy. Sci Rep 7:44978 (2017).
  29. Torres MDT, Pedron CN, Araújo I, Silva PI, Silva FD, Oliveira VX. Decoralin Analogs with Increased Resistance to Degradation and Lower Hemolytic Activity ChemistrySelect 2 (1), 18-23 (2017)
  30. Zambelli VO, Chioato L, Gutierrez VP, Ward RJ, Cury Y.Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2. J Venom Anim Toxins Incl Trop Dis. 10;23:7 (2017).

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2016

  1. Almeida D, Kitajima J, Nishiyama Jr. M, Condomitti G, Oliveira U, Setubal J, JunqueiradeAzevedo ILM. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). Mitochondrial DNA: resources in press (2016).
  2. Andrade-Silva D, Zelanis A, Kitano ES, Junqueira-de-Azevedo IL, Reis MS, Lopes AS, Serrano SM. Proteomic and glycoproteomic profilings reveal that post-translational modifications of toxins contribute to venom phenotype in snakes. J Proteome Res. 15(8):2658-75 (2016).
  3. Augusto-de-Oliveira C, Stuginski DR, Kitano ES, Andrade-Silva D, Liberato T, Fukushima I, Serrano SM, Zelanis A. Dynamic rearrangement in snake venom gland proteome: insights into Bothrops jararaca intraspecific venom variation. J Proteome Res. 15(10):3752-3762 (2016).
  4. Bernardes-Oliveira E, Gomes DL, Palomino GM, Farias KJS, Dias da Silva W, Rocha HAO, Gonçalves AK, Fernandes-Pedrosa MF, Crispim JCO. Bothrops jararaca and Bothrops erythromelas Snake Venoms Promote Cell Cycle Arrest and Induce Apoptosis via the Mitochondrial Depolarization of Cervical Cancer Cells. Evidence-Based Complementary and Alternative Medicine Volume Article ID 1574971 (2016).
  5. Bertholim L, Zelanis A, Oliveira AK, Serrano SM. Proteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase. Amino Acids 48(5):1331-5 (2016).
  6. Bosch RV, Alvarez-Flores MP, Maria DA, Chudzinski-Tavassi AM. Hemolin triggers cell survival on fibroblasts in response to serum deprivation by inhibition of apoptosis. Biomedicine & Pharmacotherapy 82: 537-546 (2016).
  7. Branco VG, Iqbal A, Alvarez-Flores MP, Sciani JM, de Andrade SA, Iwai LK, Serrano SM, Chudzinski-Tavassi AM. Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo. Biochim Biophys Acta. 1864(10):1428-35 (2016).
  8. Bressan E, Touska F, Vetter I, Kistner K, Kichko TI, Teixeira NB, Picolo G, Cury Y, Lewis RJ, Fischer MJ, Zimmermann K, Reeh PW. Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia. Pain. 157(11):2504-2516 (2016).
  9. Brigatte P, Faiad OJ, Ferreira Nocelli RC, Landgraf RG, Palma MS, Cury Y, Curi R, Sampaio SC. Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4. Mediators Inflamm. 2457532 (2016).
  10. Cajado-Carvalho D, Kuniyoshi AK, Duzzi B, Iwai LK, Oliveira ÚC, Junqueira de Azevedo IL, Kodama RT, Portaro FV. Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase. Toxins (Basel). 24;8(12): 348 (2016).
  11. Campos PF, Andrade-Silva D, Zelanis A, Paes Leme AF, Rocha MM, Menezes MC, Serrano SM, Junqueira-de-Azevedo Ide L. Trends in the evolution of snake toxins underscored by an integrative omics approach to profile the venom of the colubrid Phalotris mertensi. Genome Biol Evol. 8(8):2266-87 (2016).
  12. Carlstron JP, Verreschi DC, Batista IDC, Tsubouchi BD, de Abreu BCG, Mastantuno D, Ito DT, Ramos PW, Szczygiel NL, Chudzinski-Tavassi AM, Cruz JÁ, Barazzone GC, de Andrade AS. Segregation and packaging of Chemical Products: Deploying a Secure System in the Protein Chemistry Facility of the Laboratory of Biochemistry and Biophysics – Butantan Institute. Orbital-Electronic Journal Of Chemistry v. 8 Ed. 3 p. 218-225 (2016).
  13. Castiblanco-Valencia MM, Fraga TR, Pagotto AH, de Toledo Serrano SM, Abreu PA, Barbosa AS, Isaac L. Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion. Immunobiology 221(5):679-89 (2016).
  14. Chaparro, E.; da Silva Junior, P. I.Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis. International Journal of Antimicrobial Agents Volume: 48 Issue: 3 Pages: 277-285 Published: SEP 2016
  15. Chudzinski-Tavassi AM, Morais KL, Pacheco MT, Pasqualoto KFM, de Souza JG. Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates. Biomed Pharmacother 77:14-9. (2016). Review.
  16. Corrêa MA, Okamoto CK, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. PLoS One 11(4):e0153090 (2016).
  17. Cristina de Oliveira-Lima K, Farsky SH, Lopes PH, de Andrade RM, van den Berg CW, Tambourgi DV. Microcirculation abnormalities provoked by Loxosceles spiders’ envenomation. Toxicon 116: 35-42 (2016).
  18. de Jesus TC, Nunes VS, Lopes Mde C, Martil DE, Iwai LK, Moretti NS, Machado FC, de Lima-Stein ML, Thiemann OH, Elias MC, Janzen C, Schenkman S, da Cunha JP Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi. J Proteome Res.15(6):2039-51 (2016).
  19. de Souza JG, Morais KL, Anglés-Cano E, Boufleur P, de Mello ES, Maria DA, Origassa CS, de Campos Zampolli H, Câmara NO, Berra CM, Bosch RV, Chudzinski-Tavassi AM.Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model. Oncotarget. 20;7(38):62255-62266 (2016).
  20. Dias, Matheus H.; Kitano, Eduardo S.; Zelanis, Andre; et al.Proteomics and drug discovery in câncer. Drug Discovery Today Volume: 21 Issue: 2 Pages: 264-277 Published: FEB 2016
  21. Duzzi B, Cajado-Carvalho D, Kuniyoshi AK, Kodama RT, Gozzo FC, Fioramonte M, Tambourgi DV, Portaro FV, Rioli V. [des-Arg(1)] -Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom. Peptides 80:18-24 (2016).
  22. Elias MC, Floeter-Winter LM, Mena-Chalco JP. The dynamics of Brazilian protozoology over the past century. Mem Inst Oswaldo Cruz 111(1): 67-74 (2016).
  23. Garcia PRAF, Bicev RN, Oliveira CLP, Sant’Anna AO, Fantini MCA. Protein encapsulation in SBA-15 with expanded pores. Microporous and Mesoporous Materials 235. 59 e 68 (2016).
  24. Girard, Richard M. B. M.; Crispim, Marcell; Stolic, Ivana; et al. An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells. Antimicrobial Agents and Chemotherapy Volume: 60 Issue: 10 Pages: 5867-5877 Published: OCT 2016
  25. Guidolin FR, Caricati CP, Marcelino JR, da Silva WD. Development of Equine IgG Antivenoms against Major Snake Groups in Mozambique. PLoS Negl Trop Dis. Jan 5;10(1):e0004325 (2016).
  26. Guidolin FR, Tambourgi DV, Guidolin R, Marcelino JR, Okamoto CK, Magnoli FC, Queiroz GP, Dias da Silva W.Characterization of anti-crotalic antibodies. Toxicon. 2013 May; 66:7-17.
  27. Guirro ECBP, Perotta JH, de Paula M, Cury Y, Valadão CAA. Clinical, behavioral and antinociceptive effects of crotalphine in horses. Ciência Rural 46 (4): 694-699 (2016).
  28. Junqueira-de-Azevedo IL, Campos PF, Ching AT, Mackessy SP. Colubrid Venom Composition: An -Omics Perspective. Toxins (Basel). Review. 23;8(8):230 (2016).
  29. Leandro de Jesus TC, Calderano SG, Vitorino FN, Llanos RP, Lopes MC, de Araújo CB, Thiemman OH, Reis MD, Elias MC, Chagas da Cunha JP. Quantitative Proteomic Analysis of Replicative and Nonreplicative Forms Reveals Important Insights into Chromatin Biology of Trypanosoma cruzi. Mol Cell Mol Cell Proteomics. 16(1):23-38201 (2016).
  30. Liberato T, Troncone LR, Yamashiro ET, Serrano SM, Zelanis A. High-resolution proteomic profiling of spider venom: expanding the toxin diversity of Phoneutria nigriventer venom. Amino Acids 48(3):901-6 (2016).
  31. Lopes-Ferreira M, Sosa-Rosales I, Bruni FM, Ramos AD, Vieira Portaro FC, Conceição K, Lima C. Analysis of the intersexual variation in Thalassophryne maculosa fish venoms. Toxicon. 1;115:70-80 (2016).
  32. Menezes MC, Imbert L, Kitano ES, Vernet T, Serrano SM. Recombinant expression of the precursor of the hemorrhagic metalloproteinase HF3 and its non-catalytic domains using a cell-free synthesis system. Amino Acids. 48(9):2205-14 (2016).
  33. Morais KL, Pacheco MT, Berra CM, Bosch RV, Sciani JM, Chammas R, de Freitas Saito R, Iqbal A, Chudzinski-Tavassi AM. Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell. Mol Cell Biochem 415(1-2):119-31 (2016).
  34. Myamoto DT, Pidde-Queiroz G, Gonçalves-de-Andrade RM, Pedroso A, van den Berg CW, Tambourgi DV. Characterization of a Gene Coding for the Complement System Component FB from Loxosceles laeta Spider Venom Glands. PLoS One 11(1): e0146992 (2016).
  35. Myamoto DT, Pidde-Queiroz G, Pedroso A, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. Characterization of the gene-encoding component C3 of the complement system from the spider Loxosceles laeta venom glands: Phylogenetic implications. Immunobiology 221(9): 953–963 (2016).
  36. Pacheco MT, Morais KL, Berra CM, Demasi M, Sciani JM, Branco VG, Bosch RV, Iqbal A, Chudzinski-Tavassi AM. Specific role of cytoplasmic dynein in the mechanism of action of na antitumor molecule, Amblyomin-X. Exp Cell Res.15;340(2):248-58 (2016).
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  41. Rabaça AN, Arruda DC, Figueiredo CR, Massaoka MH, Farias CF, Tada DB, Maia VC, Silva Junior PI, Girola N, Real F, Mortara RA, Polonelli L, Travassos LR. AC‐1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model. FEBS Open Bio 6 (9), 885-901 (2016).
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  46. Silva TA, Smuczek B, Valadão IC, Dzik LM, Iglesia RP, Cruz MC, Zelanis A, de Siqueira AS, Serrano SM, Goldberg GS, Jaeger RG, Freitas VM. AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility. Oncotarget. 7(31):49998-50016 (2016).
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2015

  • Akamatsu MA, Nishiyama MY Jr, Morone M, Oliveira UC, Bezerra MF, Sakauchi MA, Raw I, Junqueira de Azevedo IL, Kitajima JP, Carvalho E, Ho PL Whole-Genome Sequence of a Bordetella pertussis Brazilian Vaccine Strain. Genome Announc. 3(1) pii: e01570-14 (2015).
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  • Almeida AM, Foronda L. Ação Educativa do Museu Histórico do Instituto Butantan: reflexões sobre os últimos três anos [Educational action of the Historical Museum of Instituto Butantan: reflexions from the last three years]. Revista Museologia & Interdisciplinaridade, 3:149-163 (2015)
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  • Campeiro JD, Neshich IP, Sant’Anna OA, Lopes R, Ianzer D, Assakura MT, Neshich G, Hayashi MA. Identification of snake bradykinin-potentiating peptides (BPPs)-simile sequences in rat brain – Potential BPP-like precursor protein? Biochem Pharmacol.2015 Jun 3. Aug 1;96(3):202-15
  • Catta-Preta CM1, Brum FL1, da Silva CC1, Zuma AA1, Elias MC2, de Souza W3, Schenkman S4, Motta MC1. Endosymbiosis in trypanosomatid protozoa: the bacterium division is controlled during the host cell cycle. Front Microbiol. 2015 Jun 2; 6:520. eCollection (2015).
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  • Costa ET, Barnabé GF, Li M, Dias AA, Machado TR, Asprino PF, Cavalher FP, Ferreira EN, Del Mar Inda M, Nagai MH, Malnic B, Duarte ML, Leite KR, de Barros AC, Carraro DM, Chammas R, Armelin HA, Cavenee W, Furnari F, Camargo AA Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals. Oncogene 34(10):1270-9 (2015).
  • Dantas WS, Marcondes JA, Shinjo SK, Perandini LA, Zambelli VO, Neves WD, Barcellos CR, Rocha MP, Yance Vdos R, Pereira RT, Murai IH, Pinto AL, Roschel H, Gualano B. GLUT4 translocation is not impaired after acute exercise in skeletal muscle of women with obesity and polycystic ovary syndrome. Obesity (Silver Spring) 23(11):2207-15 (2015).
  • de Oliveira UC, Candido DM, Coronado Dorce VA, Junqueira-de-Azevedo IL. The transcriptome recipe for the venom cocktail of Tityus bahiensis scorpion. Toxicon. 95:52-61 (2015).
  • Drewes CC, Dias RY, Branco VG, Cavalcante MF, Souza JG, Abdalla DS, Chudzinski-Tavassi AM, Farsky SH. Post-transcriptional control of Amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endotelial cells. Toxicon 101:1-10 (2015).
  • Ferreira AK, Tavares MT, Pasqualoto KF, de Azevedo RA, Teixeira SF, Ferreira- Junior WA, Bertin AM, de-Sá-Junior PL, Barbuto JA, Figueiredo CR, Cury Y, Damião MC, Parise-Filho R. RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model. Tumour Biol. 36(9):7251-67 (2015).
  • Fonseca A, Gubitoso MD, Reis MS, Sandro José de Souza SJ, Barrera J. A new approach for identification of cancer-related pathways using protein networks and genomic data. Cancer Informatics, 14 (Suppl 5), 139 (2015).
  • Freitas-de-Sousa LA, Amazonas DR, Sousa LF, Sant’Anna SS, Nishiyama MY Jr, Serrano SM, Junqueira-de-Azevedo IL, Chalkidis HM, Moura-da-Silva AM, Mourão RH. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie 118:60-70 (2015).
  • Gross ER, Zambelli VO, Ferreira JC, Small B, Chen CH. Mochly-Rosen, D. A personalized medicine approach for Asian-Americans with the aldehyde dehydrogenase 2*2 variant. Annual Review of Pharmacology and Toxicology 55: 107-27 (2015).
  • Hui Wen F, Monteiro WM, Moura da Silva AM, Tambourgi DV, Mendonça da Silva I, Sampaio VS, dos Santos MC, Sachett J, Ferreira LC, Kalil J, Lacerda M. Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis. 9(5): e0003701 (2015).
  • Iqbal A, Goldfeder MB, Marques-Porto R, Asif H, Souza JG, Faria F, Chudzinski-Tavassi AM. Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. Sci Rep. 3;7(1):1431 (2017).
  • Jared C.; Mailho-Fontana PL; Antoniazzi MM; Mendes VA; Barbaro KC; Rodrigues MT; Brodie ED. Venomous Frogs Use Heads as Weapons. Current Biology, v. 25, p. 1-5, (2015).
  • Junqueira-de-Azevedo IL, Bastos CM, Ho PL, Luna MS, Yamanouye N, Casewell NR Venom-Related Transcripts from Bothrops jararaca Tissues Provide Novel Molecular Insights into the Production and Evolution of Snake Venom. Mol Biol Evol 32(3):754-66 (2015).
  • Kimura LF, Prezotto-Neto JP, Távora BC, Faquim-Mauro EL, Pereira NA, Antoniazzi MM, Jared SG, Teixeira CF, Santoro ML, Barbaro KC. Mast cells and histamine play na important role in edema and leukocyte recruitment induced by Potamotrygon motoro stingray venom in mice. Toxicon. Sep; 103:65-73 (2015).
  • Kodama RT, Cajado-Carvalho D, Kuniyoshi AK, Kitano ES, Tashima AK, Barna BF, Takakura AC, Serrano SM, Dias-Da-Silva W, Tambourgi DV, Portaro FV. New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms. Biochim Biophys Acta – General Subjects 1850(6):1180-7 (2015).
  • Machado RJ, Junior LG, Monteiro NK, Silva-Júnior AA, Portaro FC, Barbosa EG, Braga VA, Fernandes-Pedrosa MF. Homology modeling, vasorelaxant and bradykininpotentiating activities of a novel hypotensin found in the scorpion venom from Tityus stigmurus. Toxicon Jul; 101:11-8 (2015).
  • Megale AAA, Ferreira Jr MJ, Rangel LBA, Diz MDPE, Mano MS, Hoff PMG, Lopes PH, Arai RJ, Dias da Silva W. Novel Immunogenic Epitopes in the NaPi-IIb Protein: Production of Monospecific Antibodies Using Synthetic Peptides Outlined on Isoform Specific Regions of the Type IIb Sodium-Dependent Phosphate Transporter (NaPi-IIb). Journal of Cancer Therapy 07(02):129-151 (2015).
  • Nishijima CM, Delella FK, Rodrigues CM, Rinaldo D, Lopes-Ferreira M, da Rocha LR, Vilegas W, Felisbino SL, Hiruma-Lima CA The anti-Inflammatory effects of the methanolic extract and fractions from Davilla elliptica St. Hil. (Dilleniaceae) on Bothrops jararaca envenomation. Int J. Mol. Sciences 16(6):12454-12466 (2015).
  • Paixão-Cavalcante D, Kuniyoshi AK, Portaro FC, da Silva WD, Tambourgi DV. African adders: partial characterization of snake venoms from three Bitis species of medical importance and their neutralization by experimental equine antivenoms. PLoS Negl Trop Dis 9(2):e0003419 (2015).
  • Pariona-Llanos R, Pavani RS, Reis M, Noel V, Silber AM, Armelin HA, Cano MI, Elias MC Glyceraldehyde 3-phosphate dehydrogenase-telomere association correlates with redox status in Trypanosoma cruzi. Plos One 10(3): e0120896 (2015).
  • Pedroso A, Matioli SR, Murakami MT, Pidde-Queiroz G, Tambourgi DV. Adaptive evolution in the toxicity of a spider’s venom enzymes. BMC Evol Biol 15:290 (2015).
  • Rodriguez RV, Dorce VA, de Freitas LA, Dorce AL, Lebrun I, Sobral AC, Portaro FC, Kuniyoshi AK, Carvalho DC, Nencioni AL. Intrahippocampal injection of TsTX-I increases the levels of INF-gamma in the cerebral tissue but not the levels of glutamate. Toxicon 103:155-9 (2015).
  • Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant’Anna SS, Barbaro KC, Fernandes W. Ontogenetic variation in biological activities of venoms from hybrids between Bothrops erythromelas and Bothrops neuwiedi snakes. PLoS One 10(12):e0145516 (2015).
  • Sousa LAF, Amazonas DR, Sousa LF, Sant´Anna SS, Nishiyama-Jr MY, Serrano SMT, Junqueira-De-Azevedo ILM, Chalkidis HM, Moura-Da-Silva AM, Mourão RHV. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie (Paris. Print), v. 118, p. 60-70 (2015).
  • Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-1 Presents Potent Anti-Inflammatory Activity. PLoS One 10(8):e0136116. (2015).
  • Villas Boas IM, Pidde-Queiroz G, Magnoli FC, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. A serine protease isolated from the bristles of the Amazonic caterpillar, Premolis semirufa, is a potent complement system activator. PLoS One 10(3):e0118615 (2015).
  • Wen FH, Monteiro WM, Moura da Silva AM, Tambourgi DV, da Silva IM, Sampaio VS, dos Santos MC, Sachett J, Ferreira LCL, Kalil J, Lacerda M. Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis 9(5): e0003701 (2015).
  • Zambelli VO, Chen CH, Gross ER. Reactive aldehydes: an initial path to develop precision medicine for pain control. Ann Transl Med 3(17):258 (2015).
  • Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM, Overall CM. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. J Proteomics 113:260-7 (2015).

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2014

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  • Bitencourt MAO, Lima, MCJS, Torres-Rêgo M, Fernandes JM, Silva-Junior AA, Tambourgi DV, Zucolotto SM, Fernandes-Pedrosa MF. Neutralizing Effects of Mimosa tenuiflora Extracts against Inflammation Caused by Tityus serrulatus Scorpion Venom. BioMed Research International. 2014;1-8.
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  • Calderano SG, Godoy PDM, Soares DR, Sant’Anna OA, Schenkman S, Elias MC. ORC1/CDC6 and MCM7 distinct associate with chromatin through Trypanosoma cruzi life cycle. Mol Biochem Parasitol. 2014; 193:110-113.
  • Castilho DG, Chaves AF, Xander P, Zelanis A, Kitano ES, Serrano SM, Tashima AK, Batista WL. Exploring potential virulence regulators in paracoccidioides brasiliensis isolates of varying virulence through quantitative proteomics. J Proteome Res 13(10):4259-71 (2014).
  • Chudzinski-Tavassi AM, Carvalho LCC, Alvarez-Flores MP, Andrade SA.Exogenous procoagulant factors as therapeutic and biotechnological tools. J Blood Disorders Transf. 2014 ; 5:209.
  • de Araujo, Christiane B.; Russo, Lilian C.; Castro, Leandro M.; et al.A Novel Intracellular Peptide Derived from G(1)/S Cyclin D2 Induces Cell Death. Journal of Biological Chemistry Volume: 289 Issue: 24 Pages: 16711-16726 Published: JUN 13 2014
  • Ferreira MJ, Lima C, Lopes-Ferreira M. Anti-inflammatory effect of Natterins, the major toxins from the Thalassophryne nattereri fish venom is dependent on TLR4/MyD88/PI3K signaling pathway. Toxicon (Oxford). 2014;87:54-67.
  • Herrera M, Paiva OK, Pagotto AH, Segura A, Serrano SM, Vargas M, Villalta M, Jensen SD, León G, Williams DJ, Gutiérrez JM. Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia. Am J Trop Med Hyg 91(5):887-94 (2014).
  • Lima MC, Bitencourt MA, Furtado AA, Oliveira Rocha HA, Oliveira RM, Silva Júnior AA, Tabosa do Egito ES, Tambourgi DV, Zucolotto SM, Fernandes Pedrosa MD.Ipomoea asarifolia neutralizes inflammation induced by Tityus serrulatus scorpion venom. J Ethnopharmacol. 2014 Apr 2. pii: S0378 8741(14)00250-5.
  • Lopes-Ferreira M, Gomes EM, Bruni FM, Ferreira MJ, Charvet P, Lima C. First report of interruption of mast cell degranulation and endothelial cells activation by anti-inflammatory drugs controlling the acute response provoked by Pseudoplatystoma fasciatum fish venom. Toxicon 90: 237-248 (2014).
  • Lopes-Ferreira M, Ramos AD, Martins IA, Lima C, Conceição K, Haddad Jr V. Clinical manifestations and experimental studies on the spine extract of the toadfish Porichthys porosissimus. Toxicon (Oxford). 2014;86:28-39.
  • Lopes-Ferreira, Monica; Grund, Lidiane Zito; Lima, Carla. Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system. Journal of Venomous Animals and Toxins including Tropical Diseases Volume: 20 Pages: 1-12 Published: 2014-09
  • Machado, FC. Zambelli VO. Fernandes, ACO. Heimann, AS. Cury, Y. Picolo, G. British. Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine. Journal of Pharmacology 171(4):961-72 (2014).
  • Mariano-Neto F, Matos JR, Cides Da Silva LC, Carvalho LV, Scaramuzzi K, Sant’anna OA, Oliveira CP, Fantini MCA. Physical properties of ordered mesoporous SBA-15 silica as immunological adjuvant. J. Phys. D: Appl. Phys. 47: 425402-425411 (2014).
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  • Pasqualoto KF, Balan A, Barreto SA, Simons SM, Chudzinski-Tavassi AM.Structural characterization of the cell division cycle in Strigomonas culicis, an endosymbiont-bearing trypanosomatid. Protein Pept Lett. 2014 May;21(5):452-7.
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  • Remuzgo, Cesar; Sampaio, Sandra; Picolo, Gisele; et al.Crotalphine: fluorescent analogues, structural analysis and its effect on co-cultures of peritoneal macrophages and DRG neurons. Faseb Journal Volume: 28 Issue: 1 Published: APR 2014
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  • Wlian L, Carrijo-Carvalho LC, Andrade AS, Lorenco SV, Rodrigues CJ, Maria DA, Chudzinski-Tavassi AM. Wound Healing Effects of a Lipocalin-Derived Peptide. J Clin Toxicol. 2014; 4:187.
  • Yamashiro ET, Oliveira AK, Kitano ES, Menezes MC, Junqueira-de-Azevedo IL, Paes Leme AF, Serrano SM. Proteoforms of the platelet-aggregating enzyme PA-BJ, a serine proteinase from Bothrops jararaca venom. Biochim Biophys Acta – Proteins and Proteomics 1844(12):2068-2076 (2014).
  • Zambelli VO, Fernandes AC, Gutierrez VP, Ferreira JC, Parada CA, Mochly-Rosen D, Cury Y. Peripheral sensitization increases opioid receptor expression and activation by crotalphine in rats. PLoS One. 2014 Mar 4;9(3):e90576.
  • Zambelli VO, Gross ER, Chen CH, Gutierrez VP, Cury Y, Mochly-Rosen D. Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain. Science Translational Medicine 6(251): 251ra118 (2014).
  • Zuma AA, Mendes IC, Reignault de Souza LC, Elias MC, de Souza W, Machado CR, Motta MC. How Trypanosoma cruzi handles cell cycle arrest promoted by camptothecin, a topoisomerase I inhibitor. Mol Biochem Parasitol. 2014 Feb 11. pii: S0166-6851(14)00017-6.
  • Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant’Anna SS, Barbaro KC, Fernandes W. Ontogenetic variation in biological activities of venoms from hybrids between Bothrops erythromelas and Bothrops neuwiedi snakes. PLoS One 10(12):e0145516 (2015).
  • Sousa LAF, Amazonas DR, Sousa LF, Sant´Anna SS, Nishiyama-Jr MY, Serrano SMT, Junqueira-De-Azevedo ILM, Chalkidis HM, Moura-Da-Silva AM, Mourão RHV. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie (Paris. Print), v. 118, p. 60-70 (2015).
  • Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-1 Presents Potent Anti-Inflammatory Activity. PLoS One 10(8):e0136116. (2015).
  • Villas Boas IM, Pidde-Queiroz G, Magnoli FC, Gonçalves-de-Andrade RM, van den Berg CW, Tambourgi DV. A serine protease isolated from the bristles of the Amazonic caterpillar, Premolis semirufa, is a potent complement system activator. PLoS One 10(3):e0118615 (2015).
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2013

  • Carvalho DC, Duzzi B, Kuniyoshi AK, Fioramonte M, Gozzo FC, Melo RL, Tambourgi DV, Rioli V, Portaro FC. Insights into scorpion venom peptides: alternative processing of β-KTx propeptide from Tityus serrulatus venom results in a new naturally occurring thimet oligopeptidase inhibitor. Peptides. 2013 Feb; 40:30-3.
  • da Silva MC, Lasunskaia EB, Dias da Silva W. Repeated inoculations of Mycobacterium bovis Bacille Calmette- Guérin (BCG) are needed to induce a strong humoral immune response against antigens expressed by the bacteria*. Open Journal of Immunology. 2013 ;3:71-81.
  • Da Silva, M.S.; Monteiro JP, Nunes VS, Vasconcelos EJ, Perez AM, Freitas-Junior L de H, Elias MC, Cano MI. Anucleus and kinetoplast segregation during cell cycle. PloS One. 2013 ;8:e81397.
  • Dias GS, Kitano ES, Pagotto AH, Sant’anna SS, Rocha MM, Zelanis A, Serrano SM. Individual variability in the venom proteome of juvenile Bothrops jararaca specimens.J Proteome Res. 2013 Oct 4;12(10):4585-98.
  • Fernandes de Oliveira LM, Ullah A, Masood R, Zelanis A, Spencer PJ, Serrano SM, Arni RK. Rapid purification of serine proteinases from Bothrops alternatus and Bothrops moojeni venoms. Toxicon. 2013 Dec 15; 76:282-90.
  • Frauches TS, Petretski JH, Arnholdt AC, Lasunskaia EB, de Carvalho EC, Kipnis TL, da Silva WD, Kanashiro MM. Bothropic antivenom based on monoclonal antibodies, is it possible? Toxicon. 2013 Sep; 71:49-56.
  • Grund, L.Z.; Lopes-Ferreira M.; Lima, C. The hierarchical process of differentiation of long-lived antibodysecreting cells is dependent on integrated signals derived from antigen and IL-17A. PLoS One. 2013 Sep 18;8(9):e74566.
  • Guidolin FR, Tambourgi DV, Guidolin R, Marcelino JR, Okamoto CK, Magnoli FC, Queiroz GP, Dias da Silva W.Characterization of anti-crotalic antibodies. Toxicon. 2013 May; 66:7-17.
  • Kitano ES, Garcia TC, Menezes MC, Tashima AK, Zelanis A, Serrano SM. Cotiarinase is a novel prothrombin activator from the venom of Bothrops cotiara. Biochimie. 2013 Aug;95(8):1655-9.
  • Komegae EM, Grund LZ, Lopes-Ferreira M, Lima C. Plos One. TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells. 2013;8:e71185.
  • Komegae EN, Grund LZ, Lopes-Ferreira M, Lima C. The longevity of Th2 humoral response induced by proteases natterins requires the participation of long-lasting innate-Like B cells and plasma cells in spleen. PLoS One. 2013 Jun 28;8(6):e67135.
  • LARA PG, Prudente MFS, Dias NMC, Tambourgi DV, Lino-Junior RS, Spadafora-Ferreira M, Carvalhaes MS.Analysis of Spleen Cells in Susceptible and Resistant Mice with Experimental Lagochilascariosis. ISRN Parasitology. 2013;1-8.
  • Lopes PH, Bertani R, Gonçalves-de-Andrade RM, Nagahama RH, van den Berg CW, Tambourgi DV. Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. PLoS Negl Trop Dis. 2013 Aug 22;7(8):e2394.
  • Mafra CS, Carrijo-Carvalho LC, Chudzinski-Tavassi AM, Taguchi FM, Foronda AS, Carvalho FR, de Freitas D. Antimicrobial action of biguanides on the viability of Acanthamoeba cysts and assessment of cell toxicity. Invest Ophthalmol Vis Sci. 2013 Sep 27;54(9):6363-72.
  • Maria DA, de Souza JG, Morais KL, Berra CM, Zampolli H de C, Demasi M, Simons SM, de Freitas Saito R, Chammas R, Chudzinski-Tavassi AM.A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production. Invest New Drugs. 2013 Jun;31(3):493-505.
  • Mesquita Pasqualoto KF, Carrijo-Carvalho LC, Chudzinski-Tavassi AM. Rational development of novel leads from animal secretion based on coagulation and cell targets: 1. In silico analysis to explore a peptide derivative as lipocalins’ signature. Toxicon. 2013 Jul; 69:200-10.
  • Morais KL, Mesquita Pasqualoto KF, Pacheco MTF, Berra CM, Alvarez-Flores MP, Chudzinski-Tavassi AM. Rational development of a novel TFPI-like inhibitor from Amblyomma cajennense tick. Toxin Reviews. 2013 ;33:1-
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  • Pidde-Queiroz G, Magnoli FC, Portaro FC, Serrano SM, Lopes AS, Paes Leme AF, van den Berg CW, Tambourgi DV. P-I snake venom metalloproteinase is able to activate the complemente system by direct cleavage of central components of the cascade. PLoS Negl Trop Dis. 2013;7(10):e2519.
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  • Serrano SM. The long road of research on snake venom serine proteinases. Toxicon. 2013 Feb; 62:19-26
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  • Ventura JS, Faria F, Batista IF, Simons SM, Oliveira DG, Morais KL, Chudzinski-Tavassi AM. A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis. Biomed Pharmacother. 2013 Apr;67(3):192-6.
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  • Villas-Boas IM, Gonçalves-de-Andrade RM, Squaiella-Baptistão CC, Sant’Anna OA, Tambourgi DV. Characterization of phenotypes of immune cells and cytokines associated with chronic exposure to Premolis semirufa caterpillar bristles extract. PLoS One. 2013 Sep 4;8(9):e71938.
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Pesquisadores devem fazer referência ao apoio da FAPESP de acordo com o seguinte modelo:
“Processo 2013/07467-1, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)”